Delta11-masna-kiselina desaturaza
| Delta11-masna-kiselina desaturaza | |||||||||
|---|---|---|---|---|---|---|---|---|---|
| Identifikatori | |||||||||
| EC broj | 1.14.19.5 | ||||||||
| Baze podataka | |||||||||
| IntEnz | IntEnz pregled | ||||||||
| BRENDA | BRENDA pristup | ||||||||
| ExPASy | NiceZyme pregled | ||||||||
| KEGG | KEGG pristup | ||||||||
| MetaCyc | metabolički put | ||||||||
| PRIAM | profil | ||||||||
| Strukture PBP | RCSB PDB PDBe PDBj PDBsum | ||||||||
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Delta11-masna-kiselina desaturaza (EC 1.14.19.5, Delta11 desaturaza, masno kiselinska Delta11-desaturaza, TpDESN, Cro-PG, Delta11 masno kiselinska desaturaza, Z/E11-desaturaza, Delta11-palmitoil-KoA desaturaza) je enzim sa sistematskim imenom acil-KoA,vodonik donor:kiseonik Delta11-oksidoreduktaza.[1][2][3] Ovaj enzim katalizuje sledeću hemijsku reakciju
- acil-KoA + redukovani akceptor + O2 Delta11-acil-KoA + akceptor + 2H2O
Ovaj enzim je vezan za membranu. On ima citohromu b5-sličan domen u N-terminusu i sadrži tri histidinske koji se kritične za desaturaznu aktivnost.
Reference[уреди | уреди извор]
- ^ Tonon, T., Harvey, D., Qing, R., Li, Y., Larson, T.R. and Graham, I.A. (2004). „Identification of a fatty acid Δ11-desaturase from the microalga Thalassiosira pseudonana”. FEBS Lett. 563: 28—34. PMID 15063718.
- ^ Hao, G., O'Connor, M., Liu, W. and Roelofs, W.L. (2002). „Characterization of Z/E11- and Z9-desaturases from the obliquebanded leafroller moth, Choristoneura rosaceana”. J. Insect Sci. 2:26: 1—7.
- ^ Rodriguez, F., Hallahan, D.L., Pickett, J.A. and Camps, F. (1992). „Characterization of the Δ11-palmitoyl-CoA-desaturase from Spodoptera littoralis (Lepidoptera:Noctuidae)”. Insect Biochem. Mol. Biol. 22: 143—148.
Literatura[уреди | уреди извор]
- Nicholas C. Price; Lewis Stevens (1999). Fundamentals of Enzymology: The Cell and Molecular Biology of Catalytic Proteins (Third изд.). USA: Oxford University Press. ISBN 019850229X.
- Eric J. Toone (2006). Advances in Enzymology and Related Areas of Molecular Biology, Protein Evolution (Volume 75 изд.). Wiley-Interscience. ISBN 0471205036.
- Branden C; Tooze J. Introduction to Protein Structure. New York, NY: Garland Publishing. ISBN 0-8153-2305-0.
- Irwin H. Segel. Enzyme Kinetics: Behavior and Analysis of Rapid Equilibrium and Steady-State Enzyme Systems (Book 44 изд.). Wiley Classics Library. ISBN 0471303097.
- William P. Jencks (1987). Catalysis in Chemistry and Enzymology. Dover Publications. ISBN 0486654605.
Spoljašnje veze[уреди | уреди извор]
- Delta11-fatty-acid+desaturase на US National Library of Medicine Medical Subject Headings (MeSH)
