Diftin—amonijačna ligaza
(преусмерено са Diftin-amonijak ligaza)
| Diftin—amonijačna ligaza | |||||||||
|---|---|---|---|---|---|---|---|---|---|
| Identifikatori | |||||||||
| EC broj | 6.3.1.14 | ||||||||
| CAS broj | 114514-33-9 | ||||||||
| Baze podataka | |||||||||
| IntEnz | IntEnz pregled | ||||||||
| BRENDA | BRENDA pristup | ||||||||
| ExPASy | NiceZyme pregled | ||||||||
| KEGG | KEGG pristup | ||||||||
| MetaCyc | metabolički put | ||||||||
| PRIAM | profil | ||||||||
| Strukture PBP | RCSB PDB PDBe PDBj PDBsum | ||||||||
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Diftin—amonijačna ligaza (EC 6.3.1.14, diftamidna sintaza, diftamidna sintetaza) je enzim sa sistematskim imenom diftin:amonijak ligaza (formira ADP).[1][2] Ovaj enzim katalizuje sledeću hemijsku reakciju
Ova amidaza katalizuje zadnji korak konverzije L-histidinskog ostatka u translation elongacionom faktoru eEF-2 do diftamida.
Reference[уреди | уреди извор]
- ^ Moehring, J.M. & Moehring, T.J. (1988). „The post-translational trimethylation of diphthamide studied in vitro”. J. Biol. Chem. 263: 3840—3844. PMID 3346227.
- ^ Moehring, T.J. & Moehring, J.M. (1987). „Mutant cultured cells used to study the synthesis of diphthamide”. UCLA Symp. Mol. Cell. Biol. New Ser. 45: 53—63.
Literatura[уреди | уреди извор]
- Nicholas C. Price; Lewis Stevens (1999). Fundamentals of Enzymology: The Cell and Molecular Biology of Catalytic Proteins (Third изд.). USA: Oxford University Press. ISBN 019850229X.
- Eric J. Toone (2006). Advances in Enzymology and Related Areas of Molecular Biology, Protein Evolution (Volume 75 изд.). Wiley-Interscience. ISBN 0471205036.
- Branden C; Tooze J. Introduction to Protein Structure. New York, NY: Garland Publishing. ISBN 0-8153-2305-0.
- Irwin H. Segel. Enzyme Kinetics: Behavior and Analysis of Rapid Equilibrium and Steady-State Enzyme Systems (Book 44 изд.). Wiley Classics Library. ISBN 0471303097.
- William P. Jencks (1987). Catalysis in Chemistry and Enzymology. Dover Publications. ISBN 0486654605.
Spoljašnje veze[уреди | уреди извор]
- Diphthine---ammonia+ligase на US National Library of Medicine Medical Subject Headings (MeSH)
