Manozil-oligosaharidna glukozidaza
| Manozil-oligosaharidna glukozidaza | |||||||||
|---|---|---|---|---|---|---|---|---|---|
| Identifikatori | |||||||||
| EC broj | 3.2.1.106 | ||||||||
| CAS broj | 78413-07-7 | ||||||||
| Baze podataka | |||||||||
| IntEnz | IntEnz pregled | ||||||||
| BRENDA | BRENDA pristup | ||||||||
| ExPASy | NiceZyme pregled | ||||||||
| KEGG | KEGG pristup | ||||||||
| MetaCyc | metabolički put | ||||||||
| PRIAM | profil | ||||||||
| Strukture PBP | RCSB PDB PDBe PDBj PDBsum | ||||||||
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Manozil-oligosaharidna glukozidaza (EC 3.2.1.106, Glc3Man9NAc2 oligosaharidna glukozidaza, podrezujuća glukozidaza I) je enzim sa sistematskim imenom manozil-oligosaharid glukohidrolaza.[1][2][3][4][5] Ovaj enzim katalizuje sledeću hemijsku reakciju
- eksohidroliza neredukujućih terminalnih glukoznih ostataka u manozil-oligosaharidu Glc3Man9GlcNAc2
Ovaj enzim takođe deluje u manjoj meri na korespondirajuće glikolipide i glikopeptide.
Reference[уреди | уреди извор]
- ^ Elting, J.J., Chen, W.W. and Lennarz, J. (1980). „Characterization of a glucosidase involved in an initial step in the processing of oligosaccharide chains”. J. Biol. Chem. 255: 2325—2331. PMID 7358674.
- ^ Grinna, L.S. & Robbins, P.W. (1979). „Glycoprotein biosynthesis. Rat liver microsomal glucosidases which process oligosaccharides”. J. Biol. Chem. 254: 8814—8818. PMID 479161.
- ^ Kilker, R.D., Saunier, B., Tkacz, J.S. and Herscovics, A. (1981). „Partial purification from Saccharomyces cerevisiae of a soluble glucosidase which removes the terminal glucose from the oligosaccharide Glc3Man9GlcNAc2”. J. Biol. Chem. 256: 5299—5603. PMID 7014569.
- ^ Grinna, L.S. & Robbins, P.W. (1980). „Substrate specificities of rat liver microsomal glucosidases which process glycoproteins”. J. Biol. Chem. 255: 2255—2258. PMID 7358666.
- ^ Mark, M.J. & Kornfeld, S. (1980). „Partial purification and characterization of the glucosidases involved in the processing of asparagine-linked oligosaccharides”. Arch. Biochem. Biophys. 199: 249—258. PMID 7356331.
Literatura[уреди | уреди извор]
- Nicholas C. Price; Lewis Stevens (1999). Fundamentals of Enzymology: The Cell and Molecular Biology of Catalytic Proteins (Third изд.). USA: Oxford University Press. ISBN 019850229X.
- Eric J. Toone (2006). Advances in Enzymology and Related Areas of Molecular Biology, Protein Evolution (Volume 75 изд.). Wiley-Interscience. ISBN 0471205036.
- Branden C; Tooze J. Introduction to Protein Structure. New York, NY: Garland Publishing. ISBN 0-8153-2305-0.
- Irwin H. Segel. Enzyme Kinetics: Behavior and Analysis of Rapid Equilibrium and Steady-State Enzyme Systems (Book 44 изд.). Wiley Classics Library. ISBN 0471303097.
Spoljašnje veze[уреди | уреди извор]
- Mannosyl-oligosaccharide+glucosidase на US National Library of Medicine Medical Subject Headings (MeSH)
