Molekulski šaperon Hsc70 ATPaza
| Šaperon (protein) | |||||||||
|---|---|---|---|---|---|---|---|---|---|
| Identifikatori | |||||||||
| EC broj | 3.6.4.10 | ||||||||
| Baze podataka | |||||||||
| IntEnz | IntEnz pregled | ||||||||
| BRENDA | BRENDA pristup | ||||||||
| ExPASy | NiceZyme pregled | ||||||||
| KEGG | KEGG pristup | ||||||||
| MetaCyc | metabolički put | ||||||||
| PRIAM | profil | ||||||||
| Strukture PBP | RCSB PDB PDBe PDBj PDBsum | ||||||||
| |||||||||
Šaperon (protein) (EC 3.6.4.10, molekulski šaperon Hsc70 ATPaza) je enzim sa sistematskim imenom ATP fosfohidrolaza (polimerizacija polipeptida).[1][2][3][4][5] Ovaj enzim katalizuje sledeću hemijsku reakciju
Ova veoma raznovrsna grupa enzima vrši mnoštvo funkcija koje su slične sa funkcijama šaperonina.
Reference[уреди | уреди извор]
- ^ Sadis, S. & Hightower, L.E. (1992). „Unfolded proteins stimulate molecular chaperone Hsc70 ATPase by accelerating ADP/ATP exchange”. Biochemistry. 31: 9406—9412. PMID 1356434.
- ^ Blond-Elquindi, S., Fourie, A.M., Sambrook, J.F. and Gething, M.J. (1993). „Peptide-dependent stimulation of the ATPase activity of the molecular chaperone BiP is the result of conversion of oligomers to active monomers”. J. Biol. Chem. 268: 12730—12735. PMID 8509407.
- ^ Wawrzynow, A., Wojtkowiak, D., Marszalek, J., Banecki, B., Jonsen, M., Graves, B., Georgopoulos, C. and Zylicz, M. (1995). „The ClpX heat-shock protein of Escherichia coli, the ATP-dependent substrate specificity component of the ClpP-ClpX protease, is a novel molecular chaperone”. EMBO J. 14: 1867—1877. PMID 7743994.
- ^ Sriram, M., Osipiuk, J., Freeman, B., Morimoto, R. and Joachimiak, A. (1997). „Human Hsp70 molecular chaperone binds two calcium ions within the ATPase domain”. Structure. 5: 403—414. PMID 9083109.
- ^ Li, X., Su, R.T., Hsu, H.T. and Sze, H. (1998). „The molecular chaperone calnexin associated with the vacuolar H+-ATPase from oat seedlings”. Plant Cell. 10: 119—130. PMID 9477575.
Literatura[уреди | уреди извор]
- Nicholas C. Price; Lewis Stevens (1999). Fundamentals of Enzymology: The Cell and Molecular Biology of Catalytic Proteins (Third изд.). USA: Oxford University Press. ISBN 019850229X.
- Eric J. Toone (2006). Advances in Enzymology and Related Areas of Molecular Biology, Protein Evolution (Volume 75 изд.). Wiley-Interscience. ISBN 0471205036.
- Branden C; Tooze J. Introduction to Protein Structure. New York, NY: Garland Publishing. ISBN 0-8153-2305-0.
- Irwin H. Segel. Enzyme Kinetics: Behavior and Analysis of Rapid Equilibrium and Steady-State Enzyme Systems (Book 44 изд.). Wiley Classics Library. ISBN 0471303097.
- William P. Jencks (1987). Catalysis in Chemistry and Enzymology. Dover Publications. ISBN 0486654605.
Spoljašnje veze[уреди | уреди извор]
- Non-chaperonin+molecular+chaperone+ATPase на US National Library of Medicine Medical Subject Headings (MeSH)
