N-acetilglukozamin-1-fosfodiestar a-N-acetilglukozaminidaza
| N-acetilglukozamin-1-fosfodiestar a-N-acetilglukozaminidaza | |||||||||
|---|---|---|---|---|---|---|---|---|---|
| Identifikatori | |||||||||
| EC broj | 3.1.4.45 | ||||||||
| CAS broj | 75788-84-0 | ||||||||
| Baze podataka | |||||||||
| IntEnz | IntEnz pregled | ||||||||
| BRENDA | BRENDA pristup | ||||||||
| ExPASy | NiceZyme pregled | ||||||||
| KEGG | KEGG pristup | ||||||||
| MetaCyc | metabolički put | ||||||||
| PRIAM | profil | ||||||||
| Strukture PBP | RCSB PDB PDBe PDBj PDBsum | ||||||||
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N-acetilglukozamin-1-fosfodiestar a-N-acetilglukozaminidaza (EC 3.1.4.45, alfa-N-acetilglukozaminilna fosfodiesteraza, lizozomalna alfa-N-acetilglukozaminidase, fosfodiestarska glikozidaza, alfa-N-acetil-D-glukozamin-1-fosfodiestar N-acetilglukozaminidaza, 2-acetamido-2-dezoksi-alfa-D-glukoza 1-fosfodiestar acetamidodezoksiglukohidrolaza) je enzim sa sistematskim imenom glikoprotein-N-acetil-D-glukozaminil-fosfo-D-manoza N-acetil-D-glukozaminilfosfohidrolaza.[1][2][3][4] Ovaj enzim katalizuje sledeću hemijsku reakciju
- glikoprotein N-acetil-D-glukozaminil-fosfo-D-manoza + H2O N-acetil-D-glukozamin + glikoprotein fosfo-D-manoza
Ovaj enzim deluje mnoštvo jedinjenja u kojima je N-acetil-D-glukozamin alfa-vezan za fosfatnu grupu.
Reference[уреди | уреди извор]
- ^ Van den Tweel, W.J.J., Smits, J.P., Ogg, R.L.H.P. and de Bont, J.A.M. (1988). „The involvement of an enantioselective transaminase in the metabolism of D-3- and D-4-hydroxyphenylglycine in Pseudomonas putida”. Appl. Microbiol. Biotechnol. 29: 224—230.
- ^ van der Drift, C., van Helvoort, P.E.M. and Vogels, G.D. (1971). „S-Ureidoglycolate dehydrogenase: purification and properties”. Arch. Biochem. Biophys. 145: 465—469. PMID 4399430.
- ^ van der Drift, L., Vogels, G.D. and van der Drift, C. (1975). „Allantoin racemase: a new enzyme from Pseudomonas species”. Biochim. Biophys. Acta. 391: 240—248. PMID 237557.
- ^ Waheed, A., Hasilik, A. and von Figura, K. (1981). „Processing of the phosphorylated recognition marker in lysosomal enzymes. Characterization and partial purification of a microsomal α-N-acetylglucosaminyl phosphodiesterase”. J. Biol. Chem. 256: 5717—5721. PMID 6263889.
Literatura[уреди | уреди извор]
- Nicholas C. Price; Lewis Stevens (1999). Fundamentals of Enzymology: The Cell and Molecular Biology of Catalytic Proteins (Third изд.). USA: Oxford University Press. ISBN 019850229X.
- Eric J. Toone (2006). Advances in Enzymology and Related Areas of Molecular Biology, Protein Evolution (Volume 75 изд.). Wiley-Interscience. ISBN 0471205036.
- Branden C; Tooze J. Introduction to Protein Structure. New York, NY: Garland Publishing. ISBN 0-8153-2305-0.
- Irwin H. Segel. Enzyme Kinetics: Behavior and Analysis of Rapid Equilibrium and Steady-State Enzyme Systems (Book 44 изд.). Wiley Classics Library. ISBN 0471303097.
Spoljašnje veze[уреди | уреди извор]
- N-acetylglucosamine-1-phosphodiester+alpha-N-acetylglucosaminidase на US National Library of Medicine Medical Subject Headings (MeSH)
