Peptidaza infektivnog pankreasnog nekroznog birnavirusa Vp4
Peptidaza infektivnog pankreasnog nekroznog birnavirusa Vp4 | |||||||||
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Identifikatori | |||||||||
EC broj | 3.4.21.115 | ||||||||
Baze podataka | |||||||||
IntEnz | IntEnz pregled | ||||||||
BRENDA | BRENDA pristup | ||||||||
ExPASy | NiceZyme pregled | ||||||||
KEGG | KEGG pristup | ||||||||
MetaCyc | metabolički put | ||||||||
PRIAM | profil | ||||||||
Strukture PBP | RCSB PDB PDBe PDBj PDBsum | ||||||||
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Peptidaza infektivnog pankreasnog nekroznog birnavirusa Vp4 (EC 3.4.21.115, proteaza virusa infektine pankreasne nekroze, IPNV Vp4 proteaza, IPNV Vp4 peptidaza, NS proteaza, NS-asocirana proteaza, Vp4 proteaza) je enzim.[1][2][3] Ovaj enzim katalizuje sledeću hemijsku reakciju
- Presecanje (Ser/Thr)-Xaa-Ala-(Ser/Ala)-Gly motiva u poliproteinu NH2-pVP2-VP4-VP3-COOH infektinog pankreasnog nekroznog virusa na pVP2-VP4 i VP4-VP3 spojevima
Infektivni pankreasni nekrozni virus (IPNV) je birnavirus koji uzrokuje akutnu, zaraznu bolest kod mladih pastrmki.
Reference[уреди | уреди извор]
- ^ Manning, D.S. & Leong, J.C. (1990). „Expression in Escherichia coli of the large genomic segment of infectious pancreatic necrosis virus”. Virology. 179: 16—25. PMID 2219718.
- ^ Petit, S., Lejal, N., Huet, J.C. and Delmas, B. (2000). „Active residues and viral substrate cleavage sites of the protease of the birnavirus infectious pancreatic necrosis virus”. J. Virol. 74: 2057—2066. PMID 10666235.
- ^ Dobos, P. (1995). „The molecular biology of infectious pancreatic necrosis virus (IPNV)”. Annu. Rev. Fish Dis. 5: 25—54.
Literatura[уреди | уреди извор]
- Nicholas C. Price; Lewis Stevens (1999). Fundamentals of Enzymology: The Cell and Molecular Biology of Catalytic Proteins (Third изд.). USA: Oxford University Press. ISBN 019850229X.
- Eric J. Toone (2006). Advances in Enzymology and Related Areas of Molecular Biology, Protein Evolution (Volume 75 изд.). Wiley-Interscience. ISBN 0471205036.
- Branden C; Tooze J. Introduction to Protein Structure. New York, NY: Garland Publishing. ISBN 0-8153-2305-0.
- Irwin H. Segel. Enzyme Kinetics: Behavior and Analysis of Rapid Equilibrium and Steady-State Enzyme Systems (Book 44 изд.). Wiley Classics Library. ISBN 0471303097.
- William P. Jencks (1987). Catalysis in Chemistry and Enzymology. Dover Publications. ISBN 0486654605.
Spoljašnje veze[уреди | уреди извор]
- Infectious+pancreatic+necrosis+birnavirus+Vp4+peptidase на US National Library of Medicine Medical Subject Headings (MeSH)