Serin 3-dehidrogenaza
| Serin 3-dehidrogenaza | |||||||||
|---|---|---|---|---|---|---|---|---|---|
| Identifikatori | |||||||||
| EC broj | 1.1.1.276 | ||||||||
| CAS broj | 9038-55-5 | ||||||||
| Baze podataka | |||||||||
| IntEnz | IntEnz pregled | ||||||||
| BRENDA | BRENDA pristup | ||||||||
| ExPASy | NiceZyme pregled | ||||||||
| KEGG | KEGG pristup | ||||||||
| MetaCyc | metabolički put | ||||||||
| PRIAM | profil | ||||||||
| Strukture PBP | RCSB PDB PDBe PDBj PDBsum | ||||||||
| |||||||||
Serin 3-dehidrogenaza (EC 1.1.1.276, serinska 3-dehidrogenaza) je enzim sa sistematskim imenom L-serin:NADP+ 3-oksidoreduktaza.[1][2] Ovaj enzim katalizuje sledeću hemijsku reakciju
- L-serin + NADP+ 2-amoniomalonat semialdehid + NADPH + H+
Product, 2-amonomalonat semialdehid, se spontano konvertuje u 2-aminoacetaldehid i CO2. NAD+ ne može da zameni NADP+.
Reference[уреди | уреди извор]
- ^ Fujisawa, H., Nagata, S., Chowdhury, E.K., Matsumoto, M. and Misono, H. (2002). „Cloning and sequencing of the serine dehydrogenase gene from Agrobacterium tumefaciens”. Biosci. Biotechnol. Biochem. 66: 1137—1139. PMID 12092831.
- ^ Chowdhury, E.K., Higuchi, K., Nagata, S. and Misono, H. (1997). „A novel NADP+ dependent serine dehydrogenase from Agrobacterium tumefaciens”. Biosci. Biotechnol. Biochem. 61: 152—157. PMID 9028042.
Literatura[уреди | уреди извор]
- Nicholas C. Price; Lewis Stevens (1999). Fundamentals of Enzymology: The Cell and Molecular Biology of Catalytic Proteins (Third изд.). USA: Oxford University Press. ISBN 019850229X.
- Eric J. Toone (2006). Advances in Enzymology and Related Areas of Molecular Biology, Protein Evolution (Volume 75 изд.). Wiley-Interscience. ISBN 0471205036.
- Branden C; Tooze J. Introduction to Protein Structure. New York, NY: Garland Publishing. ISBN 0-8153-2305-0.
- Irwin H. Segel. Enzyme Kinetics: Behavior and Analysis of Rapid Equilibrium and Steady-State Enzyme Systems (Book 44 изд.). Wiley Classics Library. ISBN 0471303097.
- William P. Jencks (1987). Catalysis in Chemistry and Enzymology. Dover Publications. ISBN 0486654605.
Spoljašnje veze[уреди | уреди извор]
- Serine+3-dehydrogenase на US National Library of Medicine Medical Subject Headings (MeSH)
