Steroid 17a-monooksigenaza
| Steroid 17a-monooksigenaza | |||||||||
|---|---|---|---|---|---|---|---|---|---|
| Identifikatori | |||||||||
| EC broj | 1.14.99.9 | ||||||||
| CAS broj | 9029-67-8 | ||||||||
| Baze podataka | |||||||||
| IntEnz | IntEnz pregled | ||||||||
| BRENDA | BRENDA pristup | ||||||||
| ExPASy | NiceZyme pregled | ||||||||
| KEGG | KEGG pristup | ||||||||
| MetaCyc | metabolički put | ||||||||
| PRIAM | profil | ||||||||
| Strukture PBP | RCSB PDB PDBe PDBj PDBsum | ||||||||
| |||||||||
Steroid 17a-monooksigenaza (EC 1.14.99.9, steroid 17alfa-hidroksilaza, citohrom P-45017alfa, citohrom P-450 (P-45017alfa,lijaza), 17alfa-hidroksilaza-C17,20 lijaza) je enzim sa sistematskim imenom steroid,vodonik-donor:kiseonik oksidoreduktaza (17alfa-hidroksilacija).[1][2] Ovaj enzim katalizuje sledeću hemijsku reakciju
- steroid + AH2 + O2 17alfa-hidroksisteroid + A + H2O
Za rad ovog enzima je neophodan NAD(P)H i P-450.
Reference[уреди | уреди извор]
- ^ Lynn, W.S. & Brown, R.H. (1958). „The conversion of progesterone to androgens by testes”. J. Biol. Chem. 232: 1015—1030. PMID 13549484.
- ^ Yoshida, K.-I., Oshima, H. and Troen, P. (1980). „Studies of the human testis. XIII. Properties of nicotinamide adenine dinucleotide (reduced form)-linked 17α-hydroxylation”. J. Clin. Endocrinol. Metab. 50: 895—899. PMID 6966286.
Literatura[уреди | уреди извор]
- Nicholas C. Price; Lewis Stevens (1999). Fundamentals of Enzymology: The Cell and Molecular Biology of Catalytic Proteins (Third изд.). USA: Oxford University Press. ISBN 019850229X.
- Eric J. Toone (2006). Advances in Enzymology and Related Areas of Molecular Biology, Protein Evolution (Volume 75 изд.). Wiley-Interscience. ISBN 0471205036.
- Branden C; Tooze J. Introduction to Protein Structure. New York, NY: Garland Publishing. ISBN 0-8153-2305-0.
- Irwin H. Segel. Enzyme Kinetics: Behavior and Analysis of Rapid Equilibrium and Steady-State Enzyme Systems (Book 44 изд.). Wiley Classics Library. ISBN 0471303097.
- William P. Jencks (1987). Catalysis in Chemistry and Enzymology. Dover Publications. ISBN 0486654605.
Spoljašnje veze[уреди | уреди извор]
- Steroid+17alpha-monooxygenase на US National Library of Medicine Medical Subject Headings (MeSH)
