Šablon:PBB/3630

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Insulin
Računarom-generisana slika šest insluinovih molekula u heksameru, sa naglašenom trostrukom simetrijom. Cink joni i histidin ostaci vezani za cink stabilizuju strukturu. Insulin se storira kao heksamer, dok je aktivna forma monomer [1]
Dostupne strukture
1ai0, 1aiy, 1aph, 1b17, 1b18, 1b19, 1b2a, 1b2b, 1b2c, 1b2d, 1b2e, 1b2f, 1b2g, 1b9e, 1ben, 1bph, 1cph, 1dph, 1ev3, 1ev6, 1evr, 1fu2, 1fub, 1g7a, 1g7b, 1guj, 1hiq, 1hit, 1hls, 1htv, 1iza, 1izb, 1j73, 1jca, 1jco, 1lph, 1m5a, 1mhi, 1mhj, 1mpj, 1mso, 1os3, 1os4, 1q4v, 1qiy, 1qiz, 1qj0, 1rwe, 1sf1, 1t0c, 1trz, 1tyl, 1tym, 1uz9, 1w8p, 1wav, 1xda, 1xgl, 1xw7, 1zeg, 1zeh, 1zni, 1znj, 2a3g, 2aiy, 2bn1, 2bn3, 2c8q, 2c8r, 2g4m, 2g54, 2g56, 2hiu, 2ins, 2omg, 2omh, 2omi, 2tci, 3aiy, 3ins, 3mth, 4aiy, 4ins, 5aiy, 6ins, 7ins, 9ins
Identifikatori
Simboli INS;
Vanjski ID OMIM176730 MGI96573 HomoloGene173 GeneCards: INS Gene
Pregled RNK izražavanja
PBB GE INS 206598 at tn.png
podaci
Ortolozi
Vrsta Čovek Miš
Entrez 3630 16334
Ensembl ENSG00000129965 ENSMUSG00000000215
UniProt P01308 Q5EEX1
Ref. Sekv. (iRNK) NM_000207 NM_008387
Ref. Sekv. (protein) NP_000198 NP_032413
Lokacija (UCSC) Chr 11:
2.14 - 2.14 Mb
Chr 7:
142.49 - 142.49 Mb
PubMed pretraga [1] [2]

Reference

  1. ^ PDB: 1ai0​; Chang X, Jorgensen AM, Bardrum P, Led JJ (1997). „Solution structures of the R6 human insulin hexamer,”. Biochemistry. 36 (31): 9409—22. PMID 9235985. doi:10.1021/bi9631069.