Riboflavin kinaza
| Riboflavin kinaza | |||||||||
|---|---|---|---|---|---|---|---|---|---|
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| Identifikatori | |||||||||
| EC broj | 2.7.1.26 | ||||||||
| CAS broj | 9032-82-0 | ||||||||
| Baze podataka | |||||||||
| IntEnz | IntEnz pregled | ||||||||
| BRENDA | BRENDA pristup | ||||||||
| ExPASy | NiceZyme pregled | ||||||||
| KEGG | KEGG pristup | ||||||||
| MetaCyc | metabolički put | ||||||||
| PRIAM | profil | ||||||||
| Strukture PBP | RCSB PDB PDBe PDBj PDBsum | ||||||||
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Riboflavin kinaza (EC 2.7.1.26, flavokinaza, FK, RFK) je enzim sa sistematskim imenom ATP:riboflavin 5'-fosfotransferaza.[1][2][3][4][5][6][7] Ovaj enzim katalizuje sledeću hemijsku reakciju
- ATP + riboflavin ADP + FMN
Kofaktori FMN i FAD učestvuju u brojnim procesima u svim organizmima, uključujući mitohondrijski elektronski transport, fotosintezu, masna-kiselinsku oksidaciju, i metabolizam vitamina B6, vitamina B12 i folata.
Reference[uredi | uredi izvor]
- ^ Chassy, B.M., Arsenis, C. and McCormick, D.B. (1965). „The effect of the length of the side chain of flavins on reactivity with flavokinase”. J. Biol. Chem. 240: 1338—1340. PMID 14284745.
- ^ Giri, K.V., Krishnaswamy, P.R. and Rao, N.A. (1958). „Studies on plant flavokinase”. Biochem. J. 70: 66—71. PMID 13584303.
- ^ Kearney, E.B. (1952). „The interaction of yeast flavokinase with riboflavin analogues”. J. Biol. Chem. 194: 747—754. PMID 14927668.
- ^ McCormick, D.B. & Butler, R.C. (1962). „Substrate specificity of liver flavokinase”. Biochim. Biophys. Acta. 65: 326—332.
- ^ Sandoval, F.J. & Roje, S. (2005). „An FMN hydrolase is fused to a riboflavin kinase homolog in plants”. J. Biol. Chem. 280: 38337—38345. PMID 16183635.
- ^ Solovieva, I.M., Tarasov, K.V. and Perumov, D.A. (2003). „Main physicochemical features of monofunctional flavokinase from Bacillus subtilis”. Biochemistry (Mosc). 68: 177—181. PMID 12693963.
- ^ Solovieva, I.M., Kreneva, R.A., Leak, D.J. and Perumov, D.A. (1999). „The ribR gene encodes a monofunctional riboflavin kinase which is involved in regulation of the Bacillus subtilis riboflavin operon”. Microbiology. 145: 67—73. PMID 10206712.
Literatura[uredi | uredi izvor]
- Nicholas C. Price; Lewis Stevens (1999). Fundamentals of Enzymology: The Cell and Molecular Biology of Catalytic Proteins (Third izd.). USA: Oxford University Press. ISBN 019850229X.
- Eric J. Toone (2006). Advances in Enzymology and Related Areas of Molecular Biology, Protein Evolution (Volume 75 izd.). Wiley-Interscience. ISBN 0471205036.
- Branden C; Tooze J. Introduction to Protein Structure. New York, NY: Garland Publishing. ISBN 0-8153-2305-0.
- Irwin H. Segel. Enzyme Kinetics: Behavior and Analysis of Rapid Equilibrium and Steady-State Enzyme Systems (Book 44 izd.). Wiley Classics Library. ISBN 0471303097.
- William P. Jencks (1987). Catalysis in Chemistry and Enzymology. Dover Publications. ISBN 0486654605.
Spoljašnje veze[uredi | uredi izvor]
- Riboflavin+kinase na US National Library of Medicine Medical Subject Headings (MeSH)
