4-Nitrokatehol 4-monooksigenaza
| 4-Nitrokatehol 4-monooksigenaza | |||||||||
|---|---|---|---|---|---|---|---|---|---|
| Identifikatori | |||||||||
| EC broj | 1.14.13.166 | ||||||||
| Baze podataka | |||||||||
| IntEnz | IntEnz pregled | ||||||||
| BRENDA | BRENDA pristup | ||||||||
| ExPASy | NiceZyme pregled | ||||||||
| KEGG | KEGG pristup | ||||||||
| MetaCyc | metabolički put | ||||||||
| PRIAM | profil | ||||||||
| Strukture PBP | RCSB PDB PDBe PDBj PDBsum | ||||||||
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4-Nitrokatehol 4-monooksigenaza (EC 1.14.13.166, 4-nitrokateholna 4-monooksigenaza) je enzim sa sistematskim imenom 4-nitrokatehol,NAD(P)H:kiseonik 4-oksidoreduktaza (formira 4-hidroksilacija, nitrit).[1][2][3] Ovaj enzim katalizuje sledeću hemijsku reakciju
- 4-nitrokatehol + NAD(P)H + H+ + O2 2-hidroksi-1,4-benzohinon + nitrit + NAD(P)+ + H2O
Ovaj enzim sadrži FAD. On katalizuje oksidaciju 4-nitrokatehola uz istovremeno odvajanje nitro grupe u obliku nitrita.
Reference
[уреди | уреди извор]- ^ Kadiyala, V. & Spain, J.C. (1998). „A two-component monooxygenase catalyzes both the hydroxylation of p-nitrophenol and the oxidative release of nitrite from 4-nitrocatechol in Bacillus sphaericus JS905”. Appl. Environ. Microbiol. 64: 2479—2484. PMID 9647818.
- ^ Kitagawa, W., Kimura, N. and Kamagata, Y. (2004). „A novel p-nitrophenol degradation gene cluster from a gram-positive bacterium, Rhodococcus opacus SAO101”. J. Bacteriol. 186: 4894—4902. PMID 15262926.
- ^ Zhang, J.J., Liu, H., Xiao, Y., Zhang, X.E. and Zhou, N.Y. (2009). „Identification and characterization of catabolic para-nitrophenol 4-monooxygenase and para-benzoquinone reductase from Pseudomonas sp. strain WBC-3”. J. Bacteriol. 191: 2703—2710. PMID 19218392.
Literatura
[уреди | уреди извор]- Nicholas C. Price; Lewis Stevens (1999). Fundamentals of Enzymology: The Cell and Molecular Biology of Catalytic Proteins (Third изд.). USA: Oxford University Press. ISBN 019850229X.
- Eric J. Toone (2006). Advances in Enzymology and Related Areas of Molecular Biology, Protein Evolution (Volume 75 изд.). Wiley-Interscience. ISBN 0471205036.
- Branden C; Tooze J. Introduction to Protein Structure. New York, NY: Garland Publishing. ISBN 0-8153-2305-0.
- Irwin H. Segel. Enzyme Kinetics: Behavior and Analysis of Rapid Equilibrium and Steady-State Enzyme Systems (Book 44 изд.). Wiley Classics Library. ISBN 0471303097.
Spoljašnje veze
[уреди | уреди извор]- 4-nitrocatechol+4-monooxygenase на US National Library of Medicine Medical Subject Headings (MeSH)
