Acilkarnitinska hidrolaza
| Acilkarnitinska hidrolaza | |||||||||
|---|---|---|---|---|---|---|---|---|---|
| Identifikatori | |||||||||
| EC broj | 3.1.1.28 | ||||||||
| CAS broj | 37278-42-5 | ||||||||
| Baze podataka | |||||||||
| IntEnz | IntEnz pregled | ||||||||
| BRENDA | BRENDA pristup | ||||||||
| ExPASy | NiceZyme pregled | ||||||||
| KEGG | KEGG pristup | ||||||||
| MetaCyc | metabolički put | ||||||||
| PRIAM | profil | ||||||||
| Strukture PBP | RCSB PDB PDBe PDBj PDBsum | ||||||||
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Acilkarnitinska hidrolaza (EC 3.1.1.28, HACH, karnitin estarska hidrolaza, palmitoilkarnitinska hidrolaza, palmitoil-L-karnitinska hidrolaza, dugolančana acil-L-karnitinska hidrolaza, palmitoil karnitinska hidrolaza) je enzim sa sistematskim imenom O-acilkarnitin acilhidrolaza.[1][2] Ovaj enzim katalizuje sledeću hemijsku reakciju
- O-acilkarnitin + H2O masna kiselina + L-karnitin
Ovaj enzim deluje na estre viših masnih kiselina (C6 do C18) i L-karnitin. Najaktivniji je na O-dekanoil-L-karnitinu.
Reference[уреди | уреди извор]
- ^ Mahadevan, S. & Sauer, F. (1969). „Carnitine ester hydrolase of rat liver”. J. Biol. Chem. 244: 4448—4453. PMID 5806585.
- ^ Mentlein, R., Reuter, G. and Heymann, E. (1985). „Specificity of two different purified acylcarnitine hydrolases from rat liver, their identity with other carboxylesterases, and their possible function”. Arch. Biochem. Biophys. 240: 801—810. PMID 4026306.
Literatura[уреди | уреди извор]
- Nicholas C. Price; Lewis Stevens (1999). Fundamentals of Enzymology: The Cell and Molecular Biology of Catalytic Proteins (Third изд.). USA: Oxford University Press. ISBN 019850229X.
- Eric J. Toone (2006). Advances in Enzymology and Related Areas of Molecular Biology, Protein Evolution (Volume 75 изд.). Wiley-Interscience. ISBN 0471205036.
- Branden C; Tooze J. Introduction to Protein Structure. New York, NY: Garland Publishing. ISBN 0-8153-2305-0.
- Irwin H. Segel. Enzyme Kinetics: Behavior and Analysis of Rapid Equilibrium and Steady-State Enzyme Systems (Book 44 изд.). Wiley Classics Library. ISBN 0471303097.
- William P. Jencks (1987). Catalysis in Chemistry and Enzymology. Dover Publications. ISBN 0486654605.
Spoljašnje veze[уреди | уреди извор]
- Acylcarnitine+hydrolase на US National Library of Medicine Medical Subject Headings (MeSH)
