Antranilatna sintaza

Из Википедије, слободне енциклопедије
Antranilatna sintaza
Identifikatori
EC broj 4.1.3.27
CAS broj 9031-59-8
Baze podataka
IntEnz IntEnz pregled
BRENDA BRENDA pristup
ExPASy NiceZyme pregled
KEGG KEGG pristup
MetaCyc metabolički put
PRIAM profil
Strukture PBP RCSB PDB PDBe PDBsum

Antranilatna sintaza (EC 4.1.3.27, antranilatna sintetaza, horizmatna piruvat-lijaza (amino prihvatajuća), TrpE) je enzim sa sistematskim imenom horizmat piruvat-lijaza (amino prihvatajuća; formira antranilat).[1][2][3][4][5] Ovaj enzim katalizuje sledeću hemijsku reakciju

horizmat + L-glutamin antranilat + piruvat + L-glutamat

U pojedinim organizmima ovaj enzim je deo multifunkcionalnog proteina.

Reference[уреди]

  1. Baker, T. & Crawford, I.P. (1966). „Anthranilate synthetase. Partial purification and some kinetic studies on the enzyme from Escherichia coli”. J. Biol. Chem. 241: 5577—5584. PMID 5333199. 
  2. Creighton, T.E. & Yanofsky, C. (1970). „Chorismate to tryptophan (Escherichia coli) - anthranilate synthetase, PR transferase, PRA isomerase, InGP synthetase, tryptophan synthetase”. Methods Enzymol. 17A: 365—380. 
  3. Hütter, R., Niederberger, P. and DeMoss, J.A. (1986). „Tryptophan synthetic genes in eukaryotic microorganisms”. Annu. Rev. Microbiol. 40: 55—77. PMID 3535653. 
  4. Ito, J. & Yanofsky, C. (1969). „Anthranilate synthetase, an enzyme specified by the tryptophan operon of Escherichia coli: Comparative studies on the complex and the subunits”. J. Bacteriol. 97: 734—742. PMID 4886290. 
  5. Zalkin, H. & Kling, D. (1968). „Anthranilate synthetase. Purification and properties of component I from Salmonella typhimurium”. Biochemistry. 7: 3566—3573. PMID 4878701. 

Literatura[уреди]

Spoljašnje vezе[уреди]