Endopeptidaza K
| Endopeptidaza K | |||||||||
|---|---|---|---|---|---|---|---|---|---|
 | |||||||||
| Identifikatori | |||||||||
| EC broj | 3.4.21.64 | ||||||||
| CAS broj | 39450-01-6 | ||||||||
| Baze podataka | |||||||||
| IntEnz | IntEnz pregled | ||||||||
| BRENDA | BRENDA pristup | ||||||||
| ExPASy | NiceZyme pregled | ||||||||
| KEGG | KEGG pristup | ||||||||
| MetaCyc | metabolički put | ||||||||
| PRIAM | profil | ||||||||
| Strukture PBP | RCSB PDB PDBe PDBj PDBsum | ||||||||
| |||||||||
Endopeptidaza K (EC 3.4.21.64, Tritirachium alkaline proteinaza, Tritirachium album serin proteinaza, proteinaza K, Tritirachium album proteinaza K) je enzim.[1][2][3][4][5] Ovaj enzim katalizuje sledeću hemijsku reakciju
- Hidroliza keratina, i drugih proteina sa subtilisinu sličnom specifičnošću. Dolazi do hidrolize peptidnih amida
Ovaj enzim je izolovan iz plesni Tritirachium album Limber.
Reference[уреди | уреди извор]
- ^ Ebeling, W., Hennrich, N., Klockow, M., Metz, H., Orth, H.D. and Lang, H. (1974). „Proteinase K from Tritirachium album Limber”. Eur. J. Biochem. 47: 91—97. PMID 4373242.
- ^ Morihara, K. & Tsuzuki, H. (1975). „Specificity of proteinase K from Tritirachium album Limber for synthetic peptides”. Agric. Biol. Chem. 39: 1489—1492.
- ^ Kraus, E., Klitz, H.H. and Fembert, U.F. (1976). „The specificity of proteinase K against oxidized insulin B chain”. Hoppe-Seyler's Z. Physiol. Chem. 357: 233—237. PMID 943367.
- ^ Jany, K.-D., Lederer, G. and Mayer, B. (1986). „Amino acid sequence of proteinase K from the mold Tritirachium album Limber”. FEBS Lett. 199: 139—144.
- ^ Betzel, C., Teplyakov, A.V., Harutyunyan, E.H., Saenger, W. and Wilson, K.S. (1990). „Thermitase and proteinase K: a comparison of the refined three-dimensional structures of the native enzymes”. Protein Engineering. 3: 161—172. PMID 2184432.
Literatura[уреди | уреди извор]
- Nicholas C. Price; Lewis Stevens (1999). Fundamentals of Enzymology: The Cell and Molecular Biology of Catalytic Proteins (Third изд.). USA: Oxford University Press. ISBN 019850229X.
- Eric J. Toone (2006). Advances in Enzymology and Related Areas of Molecular Biology, Protein Evolution (Volume 75 изд.). Wiley-Interscience. ISBN 0471205036.
- Branden C; Tooze J. Introduction to Protein Structure. New York, NY: Garland Publishing. ISBN 0-8153-2305-0.
- Irwin H. Segel. Enzyme Kinetics: Behavior and Analysis of Rapid Equilibrium and Steady-State Enzyme Systems (Book 44 изд.). Wiley Classics Library. ISBN 0471303097.
Spoljašnje veze[уреди | уреди извор]
- Peptidase+K на US National Library of Medicine Medical Subject Headings (MeSH)
