Indol-2-monooksigenaza
| Indol-2-monooksigenaza | |||||||||
|---|---|---|---|---|---|---|---|---|---|
| Identifikatori | |||||||||
| EC broj | 1.14.13.137 | ||||||||
| Baze podataka | |||||||||
| IntEnz | IntEnz pregled | ||||||||
| BRENDA | BRENDA pristup | ||||||||
| ExPASy | NiceZyme pregled | ||||||||
| KEGG | KEGG pristup | ||||||||
| MetaCyc | metabolički put | ||||||||
| PRIAM | profil | ||||||||
| Strukture PBP | RCSB PDB PDBe PDBj PDBsum | ||||||||
| |||||||||
Indol-2-monooksigenaza (EC 1.14.13.137, BX2 (gen), CYP71C4 (gen)) je enzim sa sistematskim imenom indol,NAD(P)H:kiseonik oksidoreduktaza (2-hidroksilacija).[1][2] Ovaj enzim katalizuje sledeću hemijsku reakciju
- indol + NAD(P)H + H+ + O2 indolin-2-on + NAD(P)+ + H2O
Ovaj enzim učestvuje u biosintezi zaštitnih i alelofatskih benzoksazinoida kod pojedinih biljaka, i.e. Iz familije Poaceae (trave). On je član grupe citohrom P450 zavisnih monooksigenaza.
Reference[уреди | уреди извор]
- ^ Frey, M., Chomet, P., Glawischnig, E., Stettner, C., Grün, S., Winklmair, A., Eisenreich, W., Bacher, A., Meeley, R.B., Briggs, S.P., Simcox, K. and Gierl, A. (1997). „Analysis of a chemical plant defense mechanism in grasses”. Science. 277: 696—699. PMID 9235894.
- ^ Glawischnig, E., Grun, S., Frey, M. and Gierl, A. (1999). „Cytochrome P450 monooxygenases of DIBOA biosynthesis: specificity and conservation among grasses”. Phytochemistry. 50: 925—930. PMID 10385992.
Literatura[уреди | уреди извор]
- Nicholas C. Price; Lewis Stevens (1999). Fundamentals of Enzymology: The Cell and Molecular Biology of Catalytic Proteins (Third изд.). USA: Oxford University Press. ISBN 019850229X.
- Eric J. Toone (2006). Advances in Enzymology and Related Areas of Molecular Biology, Protein Evolution (Volume 75 изд.). Wiley-Interscience. ISBN 0471205036.
- Branden C; Tooze J. Introduction to Protein Structure. New York, NY: Garland Publishing. ISBN 0-8153-2305-0.
- Irwin H. Segel. Enzyme Kinetics: Behavior and Analysis of Rapid Equilibrium and Steady-State Enzyme Systems (Book 44 изд.). Wiley Classics Library. ISBN 0471303097.
Spoljašnje veze[уреди | уреди извор]
- Indole-2-monooxygenase на US National Library of Medicine Medical Subject Headings (MeSH)
