Tiol S-metiltransferaza
| Tiol S-metiltransferaza | |||||||||
|---|---|---|---|---|---|---|---|---|---|
| Identifikatori | |||||||||
| EC broj | 2.1.1.9 | ||||||||
| CAS broj | 9029-81-6 | ||||||||
| Baze podataka | |||||||||
| IntEnz | IntEnz pregled | ||||||||
| BRENDA | BRENDA pristup | ||||||||
| ExPASy | NiceZyme pregled | ||||||||
| KEGG | KEGG pristup | ||||||||
| MetaCyc | metabolički put | ||||||||
| PRIAM | profil | ||||||||
| Strukture PBP | RCSB PDB PDBe PDBj PDBsum | ||||||||
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Tiol S-metiltransferaza (EC 2.1.1.9, S-metiltransferaza, tiolna metiltransferaza, TMT) je enzim sa sistematskim imenom S-adenozil-L-metionin:tiol S-metiltransferaza.[1][2][3] Ovaj enzim katalizuje sledeću hemijsku reakciju
- S-adenozil-L-metionin + tiol S-adenozil-L-homocistein + metil tioetar
Akceptori su H2S i mnoštvo alkil, aril i heterocikličnih tiola i hidroksi tiola.
Reference[уреди | уреди извор]
- ^ Borchardt, R.T. & Cheng, C.F. (1978). „Purification and characterization of rat liver microsomal thiol methyltransferase”. Biochim. Biophys. Acta. 522: 340—353. PMID 623768.
- ^ Bremer, J. & Greenberg, D.M. (1961). „Enzymic methylation of foreign sulfhydryl compounds”. Biochim. Biophys. Acta. 46: 217—224.
- ^ Weisiger, R.A. & Jakoby, W.B. (1979). „Thiol S-methyltransferase from rat liver”. Arch. Biochem. Biophys. 196: 631—637. PMID 485170.
Literatura[уреди | уреди извор]
- Nicholas C. Price; Lewis Stevens (1999). Fundamentals of Enzymology: The Cell and Molecular Biology of Catalytic Proteins (Third изд.). USA: Oxford University Press. ISBN 019850229X.
- Eric J. Toone (2006). Advances in Enzymology and Related Areas of Molecular Biology, Protein Evolution (Volume 75 изд.). Wiley-Interscience. ISBN 0471205036.
- Branden C; Tooze J. Introduction to Protein Structure. New York, NY: Garland Publishing. ISBN 0-8153-2305-0.
- Irwin H. Segel. Enzyme Kinetics: Behavior and Analysis of Rapid Equilibrium and Steady-State Enzyme Systems (Book 44 изд.). Wiley Classics Library. ISBN 0471303097.
Spoljašnje veze[уреди | уреди извор]
- Thiol+S-methyltransferase на US National Library of Medicine Medical Subject Headings (MeSH)
