Из Википедије, слободне енциклопедије
Simboli TG; AITD3; TGN
Vanjski ID OMIM188450 MGI98733 HomoloGene2430 GeneCards: TG Gene
Vrsta Čovek Miš
Entrez 7038 21819
Ensembl ENSG00000042832 ENSMUSG00000053469
UniProt P01266 O08710
RefSeq (mRNA) NM_003235 NM_009375
RefSeq (protein) NP_003226 NP_033401
Lokacija (UCSC) Chr 8:
133.88 - 134.15 Mb
Chr 15:
66.67 - 66.85 Mb
PubMed pretraga [1] [2]

Tiroglobulin (Tg) je 660 kDa, dimerini protein koji se u potpunosti formira u štitnoj žlezdi. Tiroglobulin formiraju folikularne ćelije štitne žlezde.[1][2]


  1. Knox C, Law V, Jewison T, Liu P, Ly S, Frolkis A, Pon A, Banco K, Mak C, Neveu V, Djoumbou Y, Eisner R, Guo AC, Wishart DS (2011). „DrugBank 3.0: a comprehensive resource for omics research on drugs”. Nucleic Acids Res. 39 (Database issue): D1035—41. PMC 3013709Слободан приступ. PMID 21059682. doi:10.1093/nar/gkq1126.  уреди
  2. David S. Wishart; Craig Knox; An Chi Guo; Dean Cheng; Savita Shrivastava; Dan Tzur; Bijaya Gautam; Murtaza Hassanali (2008). „DrugBank: a knowledgebase for drugs, drug actions and drug targets”. Nucleic acids research. 36 (Database issue): D901—6. PMC 2238889Слободан приступ. PMID 18048412. doi:10.1093/nar/gkm958.  уреди


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  • Bergé-Lefranc JL; Cartouzou G; Mattéi MG; et al. (1985). „Localization of the thyroglobulin gene by in situ hybridization to human chromosomes”. Hum. Genet. 69 (1): 28—31. PMID 3967888. doi:10.1007/BF00295525. 
  • Malthiéry Y, Lissitzky S (1985). „Sequence of the 5'-end quarter of the human-thyroglobulin messenger ribonucleic acid and of its deduced amino-acid sequence”. Eur. J. Biochem. 147 (1): 53—8. PMID 3971976. doi:10.1111/j.1432-1033.1985.tb08717.x. 
  • Avvedimento VE; Di Lauro R; Monticelli A; et al. (1985). „Mapping of human thyroglobulin gene on the long arm of chromosome 8 by in situ hybridization”. Hum. Genet. 71 (2): 163—6. PMID 4043966. doi:10.1007/BF00283375. 
  • Xiao S, Pollock HG, Taurog A, Rawitch AB (1995). „Characterization of hormonogenic sites in an N-terminal, cyanogen bromide fragment of human thyroglobulin”. Arch. Biochem. Biophys. 320 (1): 96—105. PMID 7793989. doi:10.1006/abbi.1995.1346. 
  • Corral J; Martín C; Pérez R; et al. (1993). „Thyroglobulin gene point mutation associated with non-endemic simple goitre”. Lancet. 341 (8843): 462—4. PMID 8094490. doi:10.1016/0140-6736(93)90209-Y. 
  • Gentile F, Salvatore G (1994). „Preferential sites of proteolytic cleavage of bovine, human and rat thyroglobulin. The use of limited proteolysis to detect solvent-exposed regions of the primary structure”. Eur. J. Biochem. 218 (2): 603—21. PMID 8269951. doi:10.1111/j.1432-1033.1993.tb18414.x. 
  • Mallet B; Lejeune PJ; Baudry N; et al. (1996). „N-glycans modulate in vivo and in vitro thyroid hormone synthesis. Study at the N-terminal domain of thyroglobulin”. J. Biol. Chem. 270 (50): 29881—8. PMID 8530385. doi:10.1074/jbc.270.50.29881. 
  • Yang SX, Pollock HG, Rawitch AB (1996). „Glycosylation in human thyroglobulin: location of the N-linked oligosaccharide units and comparison with bovine thyroglobulin”. Arch. Biochem. Biophys. 327 (1): 61—70. PMID 8615697. doi:10.1006/abbi.1996.0093. 
  • Molina F, Bouanani M, Pau B, Granier C (1996). „Characterization of the type-1 repeat from thyroglobulin, a cysteine-rich module found in proteins from different families”. Eur. J. Biochem. 240 (1): 125—33. PMID 8797845. doi:10.1111/j.1432-1033.1996.0125h.x. 

Spoljašnje veze[уреди]