Лактоил-КоА дехидратаза
| Laktoil-KoA dehidrataza | |||||||||
|---|---|---|---|---|---|---|---|---|---|
| Identifikatori | |||||||||
| EC broj | 4.2.1.54 | ||||||||
| CAS broj | 2604882 | ||||||||
| Baze podataka | |||||||||
| IntEnz | IntEnz pregled | ||||||||
| BRENDA | BRENDA pristup | ||||||||
| ExPASy | NiceZyme pregled | ||||||||
| KEGG | KEGG pristup | ||||||||
| MetaCyc | metabolički put | ||||||||
| PRIAM | profil | ||||||||
| Strukture PBP | RCSB PDB PDBe PDBj PDBsum | ||||||||
| |||||||||
Laktoil-KoA dehidrataza (EC 4.2.1.54, laktoil koenzim A dehidrataza, laktil-koenzim A dehidraza, laktil KoA dehidrataza, akrilil koenzim A hidrataza, laktoil-KoA hidrolijaza) je enzim sa sistematskim imenom (R)-laktoil-KoA hidrolijaza (formira acriloil-KoA).[1][2][3][4][5] Ovaj enzim katalizuje sledeću hemijsku reakciju
- (R)-laktoil-KoA akriloil-KoA + H2O
Bakterijski enzim učestvuje u propanoatnoj fermentaciji.
Reference[уреди | уреди извор]
- ^ Baldwin, R.L., Wood, W.A. and Emery, R.S. (1965). „Lactate metabolism by Peptostreptococcus elsdenii: evidence for lactyl coenzyme a dehydrase”. Biochim. Biophys. Acta. 97: 202—213. PMID 14292829.
- ^ Schweiger, G. & Buckel, W. (1984). „On the dehydration of (R)-lactate in the fermentation of alanine to propionate by Clostridium propionicum”. FEBS Lett. 171: 79—84. PMID 6586495.
- ^ Kuchta, R.D. & Abeles, R.H. (1985). „Lactate reduction in Clostridium propionicum. Purification and properties of lactyl-CoA dehydratase”. J. Biol. Chem. 260: 13181—13189. PMID 4055736.
- ^ Kuchta, R.D., Hanson, G.R., Holmquist, B. and Abeles, R.H. (1986). „Fe-S centers in lactyl-CoA dehydratase”. Biochemistry. 25: 7301—7307. PMID 3026450.
- ^ Hofmeister, A.E. & Buckel, W. (1992). „(R)-lactyl-CoA dehydratase from Clostridium propionicum. Stereochemistry of the dehydration of (R)-2-hydroxybutyryl-CoA to crotonyl-CoA”. Eur. J. Biochem. 206: 547—552. PMID 1597194.
Literatura[уреди | уреди извор]
- Nicholas C. Price; Lewis Stevens (1999). Fundamentals of Enzymology: The Cell and Molecular Biology of Catalytic Proteins (Third изд.). USA: Oxford University Press. ISBN 019850229X.
- Eric J. Toone (2006). Advances in Enzymology and Related Areas of Molecular Biology, Protein Evolution (Volume 75 изд.). Wiley-Interscience. ISBN 0471205036.
- Branden C; Tooze J. Introduction to Protein Structure. New York, NY: Garland Publishing. ISBN 0-8153-2305-0.
- Irwin H. Segel. Enzyme Kinetics: Behavior and Analysis of Rapid Equilibrium and Steady-State Enzyme Systems (Book 44 изд.). Wiley Classics Library. ISBN 0471303097.
Spoljašnje veze[уреди | уреди извор]
- Lactoyl-CoA+dehydratase на US National Library of Medicine Medical Subject Headings (MeSH)
