Префлагелинска пептидаза
| Preflagelinska peptidaza | |||||||||
|---|---|---|---|---|---|---|---|---|---|
| Identifikatori | |||||||||
| EC broj | 3.4.23.52 | ||||||||
| Baze podataka | |||||||||
| IntEnz | IntEnz pregled | ||||||||
| BRENDA | BRENDA pristup | ||||||||
| ExPASy | NiceZyme pregled | ||||||||
| KEGG | KEGG pristup | ||||||||
| MetaCyc | metabolički put | ||||||||
| PRIAM | profil | ||||||||
| Strukture PBP | RCSB PDB PDBe PDBj PDBsum | ||||||||
| |||||||||
Preflagelinska peptidaza (EC 3.4.23.52, FlaK) je enzim.[1][2][3] Ovaj enzim katalizuje sledeću hemijsku reakciju
- Odvaja signalni peptid sa 3 do 12 aminokiselina sa N-terminala preflagelina, obično na Arg-Gly- ili Lys-Gly-, čime se oslobađa flagelin.
Ovaj enzim je aspartička peptidaza iz Acrhaea.
Reference[уреди | уреди извор]
- ^ Bardy, S.L. & Jarrell, K.F. (2002). „FlaK of the archaeon Methanococcus maripaludis possesses preflagellin peptidase activity”. FEMS Microbiol. Lett. 208: 53—59. PMID 11934494.
- ^ Ng, S.Y., VanDyke, D.J., Chaban, B., Wu, J., Nosaka, Y., Aizawa, S. and Jarrell, K.F. (2009). „Different minimal signal peptide lengths recognized by the archaeal prepilin-like peptidases FlaK and PibD”. J. Bacteriol. 191: 6732—6740. PMID 19717585.
- ^ Hu, J., Xue, Y., Lee, S. and Ha, Y. (2011). „The crystal structure of GXGD membrane protease FlaK”. Nature. 475: 528—531. PMID 21765428.
Literatura[уреди | уреди извор]
- Nicholas C. Price; Lewis Stevens (1999). Fundamentals of Enzymology: The Cell and Molecular Biology of Catalytic Proteins (Third изд.). USA: Oxford University Press. ISBN 019850229X.
- Eric J. Toone (2006). Advances in Enzymology and Related Areas of Molecular Biology, Protein Evolution (Volume 75 изд.). Wiley-Interscience. ISBN 0471205036.
- Branden C; Tooze J. Introduction to Protein Structure. New York, NY: Garland Publishing. ISBN 0-8153-2305-0.
- Irwin H. Segel. Enzyme Kinetics: Behavior and Analysis of Rapid Equilibrium and Steady-State Enzyme Systems (Book 44 изд.). Wiley Classics Library. ISBN 0471303097.
- William P. Jencks (1987). Catalysis in Chemistry and Enzymology. Dover Publications. ISBN 0486654605.
Spoljašnje veze[уреди | уреди извор]
- Preflagellin+peptidase на US National Library of Medicine Medical Subject Headings (MeSH)
