Lupan-3beta,20-diolna sintaza
| Lupan-3beta,20-diolna sintaza | |||||||||
|---|---|---|---|---|---|---|---|---|---|
| Identifikatori | |||||||||
| EC broj | 4.2.1.128 | ||||||||
| Baze podataka | |||||||||
| IntEnz | IntEnz pregled | ||||||||
| BRENDA | BRENDA pristup | ||||||||
| ExPASy | NiceZyme pregled | ||||||||
| KEGG | KEGG pristup | ||||||||
| MetaCyc | metabolički put | ||||||||
| PRIAM | profil | ||||||||
| Strukture PBP | RCSB PDB PDBe PDBj PDBsum | ||||||||
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Lupan-3beta,20-diolna sintaza (EC 4.2.1.128, LUP1 (gen)) je enzim sa sistematskim imenom (3S)-2,3-epoksi-2,3-dihidroskvalen hidrolijaza (formira lupan-3beta,20-diol).[1][2] Ovaj enzim katalizuje sledeću hemijsku reakciju
- lupan-3beta,20-diol (3S)-2,3-epoksi-2,3-dihidroskvalen + H2O
Ovaj reakcija se odvija u reverznom smeru.
Reference[uredi | uredi izvor]
- ^ Segura, M.J., Meyer, M.M. and Matsuda, S.P. (2000). „Arabidopsis thaliana LUP1 converts oxidosqualene to multiple triterpene alcohols and a triterpene diol”. Org. Lett. 2: 2257—2259. PMID 10930257.
- ^ Kushiro, T., Hoshino, M., Tsutsumi, T., Kawai, K., Shiro, M., Shibuya, M. and Ebizuka, Y. (2006). „Stereochemical course in water addition during LUP1-catalyzed triterpene cyclization”. Org. Lett. 8: 5589—5592. PMID 17107079.
Literatura[uredi | uredi izvor]
- Nicholas C. Price; Lewis Stevens (1999). Fundamentals of Enzymology: The Cell and Molecular Biology of Catalytic Proteins (Third izd.). USA: Oxford University Press. ISBN 019850229X.
- Eric J. Toone (2006). Advances in Enzymology and Related Areas of Molecular Biology, Protein Evolution (Volume 75 izd.). Wiley-Interscience. ISBN 0471205036.
- Branden C; Tooze J. Introduction to Protein Structure. New York, NY: Garland Publishing. ISBN 0-8153-2305-0.
- Irwin H. Segel. Enzyme Kinetics: Behavior and Analysis of Rapid Equilibrium and Steady-State Enzyme Systems (Book 44 izd.). Wiley Classics Library. ISBN 0471303097.
Spoljašnje veze[uredi | uredi izvor]
- Lupan-3beta,20-diol+synthase na US National Library of Medicine Medical Subject Headings (MeSH)
