Fosfatidil-N-metiltanolamin N-metiltransferaza
| Fosfatidil-N-metiltanolamin N-metiltransferaza | |||||||||
|---|---|---|---|---|---|---|---|---|---|
| Identifikatori | |||||||||
| EC broj | 2.1.1.71 | ||||||||
| CAS broj | 67167-73-1 | ||||||||
| Baze podataka | |||||||||
| IntEnz | IntEnz pregled | ||||||||
| BRENDA | BRENDA pristup | ||||||||
| ExPASy | NiceZyme pregled | ||||||||
| KEGG | KEGG pristup | ||||||||
| MetaCyc | metabolički put | ||||||||
| PRIAM | profil | ||||||||
| Strukture PBP | RCSB PDB PDBe PDBj PDBsum | ||||||||
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Fosfatidil-N-metiltanolamin N-metiltransferaza (EC 2.1.1.71, fosfatidilmonometiltanolaminska metiltransferaza, metiltransferaza II, fosfolipidna metiltransferaza, PLMT, fosfatidil-N-metiltanolaminska metiltransferaza, fosfatidil-N-monometiltanolaminska metiltransferaza, fosfatidiletanolaminska metiltransferaza I, fosfatidilmonometiltanolaminska metiltransferaza) je enzim sa sistematskim imenom S-adenozil-L-metionin:fosfatidil-N-metiltanolamin N-metiltransferaza.[1][2] Ovaj enzim katalizuje sledeću hemijsku reakciju
- S-adenozil-L-metionin + fosfatidil-N-metiletanolamin S-adenozil-L-homocistein + fosfatidil-N-dimetiletanolamin
Enzim takođe katalizuje transfer dodatne metil grupe, čime se formira fosfatidilholin.
Reference[уреди | уреди извор]
- ^ Hirata, F., Viveros, O.H., Diliberto, E.J., Jr. and Axelrod, J. (1978). „Identification and properties of two methyltransferases in conversion of phosphatidylethanolamine to phosphatidylcholine”. Proc. Natl. Acad. Sci. USA. 75: 1718—1721. PMID 25437.
- ^ Schneider, W.J. & Vance, D.E. (1979). „Conversion of phosphatidylethanolamine to phosphatidylcholine in rat liver. Partial purification and characterization of the enzymatic activities”. J. Biol. Chem. 254: 3886—3891. PMID 438165.
Literatura[уреди | уреди извор]
- Nicholas C. Price; Lewis Stevens (1999). Fundamentals of Enzymology: The Cell and Molecular Biology of Catalytic Proteins (Third изд.). USA: Oxford University Press. ISBN 019850229X.
- Eric J. Toone (2006). Advances in Enzymology and Related Areas of Molecular Biology, Protein Evolution (Volume 75 изд.). Wiley-Interscience. ISBN 0471205036.
- Branden C; Tooze J. Introduction to Protein Structure. New York, NY: Garland Publishing. ISBN 0-8153-2305-0.
- Irwin H. Segel. Enzyme Kinetics: Behavior and Analysis of Rapid Equilibrium and Steady-State Enzyme Systems (Book 44 изд.). Wiley Classics Library. ISBN 0471303097.
- William P. Jencks (1987). Catalysis in Chemistry and Enzymology. Dover Publications. ISBN 0486654605.
Spoljašnje veze[уреди | уреди извор]
- Phosphatidyl-N-methylethanolamine+N-methyltransferase на US National Library of Medicine Medical Subject Headings (MeSH)
