Presilfiperfolanolna sintaza
Presilfiperfolanolna sintaza | |||||||||
---|---|---|---|---|---|---|---|---|---|
Identifikatori | |||||||||
EC broj | 4.2.3.74 | ||||||||
Baze podataka | |||||||||
IntEnz | IntEnz pregled | ||||||||
BRENDA | BRENDA pristup | ||||||||
ExPASy | NiceZyme pregled | ||||||||
KEGG | KEGG pristup | ||||||||
MetaCyc | metabolički put | ||||||||
PRIAM | profil | ||||||||
Strukture PBP | RCSB PDB PDBe PDBj PDBsum | ||||||||
|
Presilfiperfolanolna sintaza (EC 4.2.3.74, BcBOT2, CND15) je enzim sa sistematskim imenom (2E,6E)-farnezil-difosfat difosfohidrolaza (formira presilfiperfolan-8beta-ol).[1][2] Ovaj enzim katalizuje sledeću hemijsku reakciju
- (2E,6E)-farnezil difosfat + H2O presilfiperfolan-8beta-ol + difosfat
Za dejstvo ovog enzima je neophodan jon Mg2+.
Reference[уреди | уреди извор]
- ^ Pinedo, C., Wang, C.M., Pradier, J.M., Dalmais, B., Choquer, M., Le Pecheur, P., Morgant, G., Collado, I.G., Cane, D.E. and Viaud, M. (2008). „Sesquiterpene synthase from the botrydial biosynthetic gene cluster of the phytopathogen Botrytis cinerea”. ACS Chem. Biol. 3: 791—801. PMID 19035644.
- ^ Wang, C.M., Hopson, R., Lin, X. and Cane, D.E. (2009). „Biosynthesis of the sesquiterpene botrydial in Botrytis cinerea. Mechanism and stereochemistry of the enzymatic formation of presilphiperfolan-8β-ol”. J. Am. Chem. Soc. 131: 8360—8361. PMID 19476353.
Literatura[уреди | уреди извор]
- Nicholas C. Price; Lewis Stevens (1999). Fundamentals of Enzymology: The Cell and Molecular Biology of Catalytic Proteins (Third изд.). USA: Oxford University Press. ISBN 019850229X.
- Eric J. Toone (2006). Advances in Enzymology and Related Areas of Molecular Biology, Protein Evolution (Volume 75 изд.). Wiley-Interscience. ISBN 0471205036.
- Branden C; Tooze J. Introduction to Protein Structure. New York, NY: Garland Publishing. ISBN 0-8153-2305-0.
- Irwin H. Segel. Enzyme Kinetics: Behavior and Analysis of Rapid Equilibrium and Steady-State Enzyme Systems (Book 44 изд.). Wiley Classics Library. ISBN 0471303097.
Spoljašnje veze[уреди | уреди извор]
- Presilphiperfolanol+synthase на US National Library of Medicine Medical Subject Headings (MeSH)