Ruselizin
| Ruselizin | |||||||||
|---|---|---|---|---|---|---|---|---|---|
| Identifikatori | |||||||||
| EC broj | 3.4.24.58 | ||||||||
| CAS broj | 79393-92-3 | ||||||||
| Baze podataka | |||||||||
| IntEnz | IntEnz pregled | ||||||||
| BRENDA | BRENDA pristup | ||||||||
| ExPASy | NiceZyme pregled | ||||||||
| KEGG | KEGG pristup | ||||||||
| MetaCyc | metabolički put | ||||||||
| PRIAM | profil | ||||||||
| Strukture PBP | RCSB PDB PDBe PDBj PDBsum | ||||||||
| |||||||||
Ruselizin (EC 3.4.24.58, Russell's viper venomni faktor X aktivator, RVV-X, krvno-koagulacioni faktor X aktivacioni enzim, metaloproteinaza RVV-x, Vipera russelli proteinaza, Russell's viper krvno koagulacioni faktor X activator, RVV-V) je enzim.[1][2][3] Ovaj enzim katalizuje sledeću hemijsku reakciju
- Specifično aktivira nekoliko komponenti sistema zgrušavanja krvi, uključujući koagulacioni faktor X, koagulacioni faktor IX i protein C putem razlaganja -Arg- veza. Ne deluje na insulinski B lanac
Ovaj enzim je prisutanu venumu zmije Vipera russelli.
Reference[уреди | уреди извор]
- ^ Furie, B.C. & Furie, B. (1976). „Coagulant protein of Russell's viper venom”. Methods Enzymol. 45: 191—205. PMID 1011991.
- ^ Lindquist, P.A., Fujikawa, K. and Davie, E.W. (1978). „Activation of bovine factor IX (Christmas factor) by factor XIa (activated plasma thromboplastin antecent) and a protease from Russell's viper venom”. J. Biol. Chem. 253: 1902—1909. PMID 632245.
- ^ Takeya, H., Nishida, S., Miyata, T., Kawada, S., Saisaka, Y., Morita, T. and Iwanaga, S. (1992). „Coagulation factor X activating enzyme from Russell's viper venom (RVV-X). A novel metalloproteinase with disintegrin (platelet aggregation inhibitor)-like and C-type lectin-like domains”. J. Biol. Chem. 267: 14109—14117. PMID 1629211.
Literatura[уреди | уреди извор]
- Nicholas C. Price; Lewis Stevens (1999). Fundamentals of Enzymology: The Cell and Molecular Biology of Catalytic Proteins (Third изд.). USA: Oxford University Press. ISBN 019850229X.
- Eric J. Toone (2006). Advances in Enzymology and Related Areas of Molecular Biology, Protein Evolution (Volume 75 изд.). Wiley-Interscience. ISBN 0471205036.
- Branden C; Tooze J. Introduction to Protein Structure. New York, NY: Garland Publishing. ISBN 0-8153-2305-0.
- Irwin H. Segel. Enzyme Kinetics: Behavior and Analysis of Rapid Equilibrium and Steady-State Enzyme Systems (Book 44 изд.). Wiley Classics Library. ISBN 0471303097.
Spoljašnje veze[уреди | уреди извор]
- Russellysin на US National Library of Medicine Medical Subject Headings (MeSH)
