3-Okso-5,6-dehidrosuberil-KoA semialdehid dehidrogenaza
| 3-Okso-5,6-dehidrosuberil-KoA semialdehid dehidrogenaza | |||||||||
|---|---|---|---|---|---|---|---|---|---|
| Identifikatori | |||||||||
| EC broj | 1.17.1.7 | ||||||||
| Baze podataka | |||||||||
| IntEnz | IntEnz pregled | ||||||||
| BRENDA | BRENDA pristup | ||||||||
| ExPASy | NiceZyme pregled | ||||||||
| KEGG | KEGG pristup | ||||||||
| MetaCyc | metabolički put | ||||||||
| PRIAM | profil | ||||||||
| Strukture PBP | RCSB PDB PDBe PDBj PDBsum | ||||||||
| |||||||||
3-Okso-5,6-dehidrosuberil-KoA semialdehid dehidrogenaza (EC 1.17.1.7, paaZ (gen)) je enzim sa sistematskim imenom 3-okso-5,6-dehidrosuberil-KoA semialdehid:NADP+ oksidoreduktaza.[1][2][3] Ovaj enzim katalizuje sledeću hemijsku reakciju
- 3-okso-5,6-dehidrosuberil-KoA semialdehid + NADP+ + H2O 3-okso-5,6-dehidrosuberil-KoA + NADPH + H+
Enzim iz Escherichia coli je bifunkcionalni protein koji takođe katalizuje reakciju enzima EC 3.7.1.16, oksepin-KoA hidrolaze.
Reference[уреди | уреди извор]
- ^ Ferrandez, A., Minambres, B., Garcia, B., Olivera, E.R., Luengo, J.M., Garcia, J.L. and Diaz, E. (1998). „Catabolism of phenylacetic acid in Escherichia coli. Characterization of a new aerobic hybrid pathway”. J. Biol. Chem. 273: 25974—25986. PMID 9748275.
- ^ Ismail, W., El-Said Mohamed, M., Wanner, B.L., Datsenko, K.A., Eisenreich, W., Rohdich, F., Bacher, A. and Fuchs, G. (2003). „Functional genomics by NMR spectroscopy. Phenylacetate catabolism in Escherichia coli”. Eur. J. Biochem. 270: 3047—3054. PMID 12846838.
- ^ Teufel, R., Mascaraque, V., Ismail, W., Voss, M., Perera, J., Eisenreich, W., Haehnel, W. and Fuchs, G. (2010). „Bacterial phenylalanine and phenylacetate catabolic pathway revealed”. Proc. Natl. Acad. Sci. USA. 107: 14390—14395. PMID 20660314.
Literatura[уреди | уреди извор]
- Nicholas C. Price; Lewis Stevens (1999). Fundamentals of Enzymology: The Cell and Molecular Biology of Catalytic Proteins (Third изд.). USA: Oxford University Press. ISBN 019850229X.
- Eric J. Toone (2006). Advances in Enzymology and Related Areas of Molecular Biology, Protein Evolution (Volume 75 изд.). Wiley-Interscience. ISBN 0471205036.
- Branden C; Tooze J. Introduction to Protein Structure. New York, NY: Garland Publishing. ISBN 0-8153-2305-0.
- Irwin H. Segel. Enzyme Kinetics: Behavior and Analysis of Rapid Equilibrium and Steady-State Enzyme Systems (Book 44 изд.). Wiley Classics Library. ISBN 0471303097.
Spoljašnje veze[уреди | уреди извор]
- 3-oxo-5,6-dehydrosuberyl-CoA+semialdehyde+dehydrogenase на US National Library of Medicine Medical Subject Headings (MeSH)
