6-hidroksipseudooksinikotin dehidrogenaza
| 6-hidroksipseudooksinikotin dehidrogenaza | |||||||||
|---|---|---|---|---|---|---|---|---|---|
| Identifikatori | |||||||||
| EC broj | 1.5.99.14 | ||||||||
| Baze podataka | |||||||||
| IntEnz | IntEnz pregled | ||||||||
| BRENDA | BRENDA pristup | ||||||||
| ExPASy | NiceZyme pregled | ||||||||
| KEGG | KEGG pristup | ||||||||
| MetaCyc | metabolički put | ||||||||
| PRIAM | profil | ||||||||
| Strukture PBP | RCSB PDB PDBe PDBj PDBsum | ||||||||
| |||||||||
6-hidroksipseudooksinikotin dehidrogenaza (EC 1.5.99.14, 6-hidroksipseudooksinikotinska dehidrogenaza) je enzim sa sistematskim imenom 1-(6-hidroksipiridin-3-il)-4-(metilamino)butan-1-on:akceptor 6-oksidoreduktaza (hidroksilacija).[1][2][3] Ovaj enzim katalizuje sledeću hemijsku reakciju:
- 1-(6-hidroksipiridin-3-il)-4-(metilamino)butan-1-on + akceptor + H2O 1-(2,6-dihidroksipiridin-3-il)-4-(metilamino)butan-1-on + redukovani akceptor
Ovaj enzim sadrži citidilil molibdenijum kofaktor.
Reference
[уреди | уреди извор]- ^ Freudenberg, W., Konig, K. and Andreesen, J. R. (1988). „Nicotine dehydrogenase from Arthrobacter oxidans: A molybdenum-containing hydroxylase”. FEMS Microbiology Letters. 52: 13—18.
- ^ Grether-Beck, S., Igloi, G.L., Pust, S., Schilz, E., Decker, K. and Brandsch, R. (1994). „Structural analysis and molybdenum-dependent expression of the pAO1-encoded nicotine dehydrogenase genes of Arthrobacter nicotinovorans”. Mol. Microbiol. 13: 929—936. PMID 7815950.
- ^ Sachelaru, P., Schiltz, E. and Brandsch, R. (2006). „A functional mobA gene for molybdopterin cytosine dinucleotide cofactor biosynthesis is required for activity and holoenzyme assembly of the heterotrimeric nicotine dehydrogenases of Arthrobacter nicotinovorans”. Appl. Environ. Microbiol. 72: 5126—5131. PMID 16820521.
Literatura
[уреди | уреди извор]- Nicholas C. Price; Lewis Stevens (1999). Fundamentals of Enzymology: The Cell and Molecular Biology of Catalytic Proteins (Third изд.). USA: Oxford University Press. ISBN 019850229X.
- Eric J. Toone (2006). Advances in Enzymology and Related Areas of Molecular Biology, Protein Evolution (Volume 75 изд.). Wiley-Interscience. ISBN 0471205036.
- Branden C; Tooze J. Introduction to Protein Structure. New York, NY: Garland Publishing. ISBN 0-8153-2305-0.
- Irwin H. Segel. Enzyme Kinetics: Behavior and Analysis of Rapid Equilibrium and Steady-State Enzyme Systems (Book 44 изд.). Wiley Classics Library. ISBN 0471303097.
Spoljašnje veze
[уреди | уреди извор]- 6-hydroxypseudooxynicotine+dehydrogenase на US National Library of Medicine Medical Subject Headings (MeSH)
