Citozol-alanilna aminopeptidaza
| Citozol-alanilna aminopeptidaza | |||||||||
|---|---|---|---|---|---|---|---|---|---|
| Identifikatori | |||||||||
| EC broj | 3.4.11.14 | ||||||||
| CAS broj | 243859-94-1 | ||||||||
| Baze podataka | |||||||||
| IntEnz | IntEnz pregled | ||||||||
| BRENDA | BRENDA pristup | ||||||||
| ExPASy | NiceZyme pregled | ||||||||
| KEGG | KEGG pristup | ||||||||
| MetaCyc | metabolički put | ||||||||
| PRIAM | profil | ||||||||
| Strukture PBP | RCSB PDB PDBe PDBj PDBsum | ||||||||
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Citozol-alanilna aminopeptidaza (EC 3.4.11.14, arilamidaza, aminopolipeptidaza, tiol-aktivirana aminopeptidaza, aminopeptidaza ljudske jetre, puromicin-senzitivna aminopeptidaza, aminopeptidaza rastvornog alanila, citosolna aminopeptidaza III, alaninska aminopeptidaza) je enzim.[1][2][3] Ovaj enzim katalizuje sledeću hemijsku reakciju
- Odvajanje N-terminalne aminokiseline, preferentno alanina, sa širokog opsega peptida, amida i arilamida
Ovaj enzim je senzitivan na puromicin. Za njegov rad je neophodan jon Co2+.
Reference[уреди | уреди извор]
- ^ Starnes, W.L. & Behal, F.J. (1974). „A human liver aminopeptidase. The amino acid and carbohydrate content, and some physical properties of a sialic acid containing glycoprotein”. Biochemistry. 13: 3221—3227. PMID 4841062.
- ^ Kao, Y.J., Starnes, W.L. and Behal, F.J. (1978). „Human kidney alanine aminopeptidase: physical and kinetic properties of a sialic acid containing glycoprotein”. Biochemistry. 17: 2990—2994. PMID 698181.
- ^ Sidorowicz, W., Hsia, W.-C., Maslej-Zownir, M. and Behal, F.J. (1980). „Multiple molecular forms of human alanine aminopeptidase: imunochemical properties”. Clin. Chim. Acta. 107: 245—256. PMID 6108169.
Literatura[уреди | уреди извор]
- Nicholas C. Price; Lewis Stevens (1999). Fundamentals of Enzymology: The Cell and Molecular Biology of Catalytic Proteins (Third изд.). USA: Oxford University Press. ISBN 019850229X.
- Eric J. Toone (2006). Advances in Enzymology and Related Areas of Molecular Biology, Protein Evolution (Volume 75 изд.). Wiley-Interscience. ISBN 0471205036.
- Branden C; Tooze J. Introduction to Protein Structure. New York, NY: Garland Publishing. ISBN 0-8153-2305-0.
- Irwin H. Segel. Enzyme Kinetics: Behavior and Analysis of Rapid Equilibrium and Steady-State Enzyme Systems (Book 44 изд.). Wiley Classics Library. ISBN 0471303097.
Spoljašnje veze[уреди | уреди извор]
- Cytosol+alanyl+aminopeptidase на US National Library of Medicine Medical Subject Headings (MeSH)
