Deuterolizin
| Deuterolizin | |||||||||
|---|---|---|---|---|---|---|---|---|---|
| Identifikatori | |||||||||
| EC broj | 3.4.24.39 | ||||||||
| CAS broj | 247028-11-1 | ||||||||
| Baze podataka | |||||||||
| IntEnz | IntEnz pregled | ||||||||
| BRENDA | BRENDA pristup | ||||||||
| ExPASy | NiceZyme pregled | ||||||||
| KEGG | KEGG pristup | ||||||||
| MetaCyc | metabolički put | ||||||||
| PRIAM | profil | ||||||||
| Strukture PBP | RCSB PDB PDBe PDBj PDBsum | ||||||||
| |||||||||
Deuterolizin (EC 3.4.24.39, Penicillium roqueforti proteaza II, mikrobna neutralna proteinaza II, kiselinska metaloproteinaza, neutralna proteinaza II, Penicillium roqueforti metaloproteinaza) je enzim.[1][2][3][4][5] Ovaj enzim katalizuje sledeću hemijsku reakciju
- Preferentno razlaanje veza sa hidrofobnim ostacima u P1'; takođe Asn3-Gln i Gly8-Ser veza u lancu insulina B
Ovaj enzim je prisutan u Penicillium roqueforti, P. caseicolum, Aspergillus sojae i A. Oryzae.
Reference[уреди | уреди извор]
- ^ Nakadai, T., Nasuno, S. and Iguchi, N. (1973). „Purification and properties of neutral proteinase II from Aspergillus oryzae”. Agric. Biol. Chem. 37: 2703—2708.
- ^ Gripon, J.-C. & Hermier, J. (1974). „Le système protéolytique de Penicillium roqueforti. III. Purification, propriétés et spécificité d’une protéase inhibée par l’E.D.T.A”. Biochimie. 56: 1324—1332. PMID 4219726.
- ^ Sekine, H. (1976). „, Neutral proteinases I and II of Aspergillus sojae action on various substrates”. Agric. Biol. Chem. 40: 703—709.
- ^ Gripon, J.C., Auberger, B. and Lenoir, J. (1980). „Metalloproteases from Penicillium caseicolum and P. roqueforti: comparision of specificity and chemical characterization”. Int. J. Biochem. 12: 451—455. PMID 6998789.
- ^ Vaganova, T.I., Ivanova, N.M. and Stepanov, V.M. (1988). „Isolation and properties of the "acid" metalloproteinase from Aspergillus oryzae”. Biochemistry (Mosc). 53: 1171—1178.
Literatura[уреди | уреди извор]
- Nicholas C. Price; Lewis Stevens (1999). Fundamentals of Enzymology: The Cell and Molecular Biology of Catalytic Proteins (Third изд.). USA: Oxford University Press. ISBN 019850229X.
- Eric J. Toone (2006). Advances in Enzymology and Related Areas of Molecular Biology, Protein Evolution (Volume 75 изд.). Wiley-Interscience. ISBN 0471205036.
- Branden C; Tooze J. Introduction to Protein Structure. New York, NY: Garland Publishing. ISBN 0-8153-2305-0.
- Irwin H. Segel. Enzyme Kinetics: Behavior and Analysis of Rapid Equilibrium and Steady-State Enzyme Systems (Book 44 изд.). Wiley Classics Library. ISBN 0471303097.
- William P. Jencks (1987). Catalysis in Chemistry and Enzymology. Dover Publications. ISBN 0486654605.
Spoljašnje veze[уреди | уреди извор]
- Deuterolysin на US National Library of Medicine Medical Subject Headings (MeSH)
