Dugolančana-masna-acil-KoA reduktaza
| Dugolančana-masna-acil-KoA reduktaza | |||||||||
|---|---|---|---|---|---|---|---|---|---|
| Identifikatori | |||||||||
| EC broj | 1.2.1.50 | ||||||||
| CAS broj | 50936-56-6 | ||||||||
| Baze podataka | |||||||||
| IntEnz | IntEnz pregled | ||||||||
| BRENDA | BRENDA pristup | ||||||||
| ExPASy | NiceZyme pregled | ||||||||
| KEGG | KEGG pristup | ||||||||
| MetaCyc | metabolički put | ||||||||
| PRIAM | profil | ||||||||
| Strukture PBP | RCSB PDB PDBe PDBj PDBsum | ||||||||
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Dugolančana-masna-acil-KoA reduktaza (EC 1.2.1.50, acil-KoA reduktaza, acil koenzim A reduktaza) je enzim sa sistematskim imenom dugolančani aldehid:NADP+ oksidoreduktaza (formira acil-KoA).[1][2] Ovaj enzim katalizuje sledeću hemijsku reakciju
- dugolančani aldehid + KoA + NADP+ dugolančani acil-KoA + NADPH + H+
Zajedno sa EC 6.2.1.19, ligazom dugolančane masne-kiseline---luciferin-komponente, formira reduktazni sistem masnih kiselina koji formura supstrat za EC 1.14.14.3, alkanalnu monooksigenazu (FMN-vezanu). Ona je deo bakterijskog luciferaznog sistema.
Reference[уреди | уреди извор]
- ^ Riendeau, D., Rodrigues, A. and Meighen, E. (1982). „Resolution of the fatty acid reductase from Photobacterium phosphoreum into acyl protein synthetase and acyl-CoA reductase activities. Evidence for an enzyme complex”. J. Biol. Chem. 257: 6908—6915. PMID 7085612.
- ^ Wall, L. & Meighen, E.A. (1986). „Subunit structure of the fatty-acid reductase complex from Photobacterium phosphoreum”. Biochemistry. 25: 4315—4321.
Literatura[уреди | уреди извор]
- Nicholas C. Price; Lewis Stevens (1999). Fundamentals of Enzymology: The Cell and Molecular Biology of Catalytic Proteins (Third изд.). USA: Oxford University Press. ISBN 019850229X.
- Eric J. Toone (2006). Advances in Enzymology and Related Areas of Molecular Biology, Protein Evolution (Volume 75 изд.). Wiley-Interscience. ISBN 0471205036.
- Branden C; Tooze J. Introduction to Protein Structure. New York, NY: Garland Publishing. ISBN 0-8153-2305-0.
- Irwin H. Segel. Enzyme Kinetics: Behavior and Analysis of Rapid Equilibrium and Steady-State Enzyme Systems (Book 44 изд.). Wiley Classics Library. ISBN 0471303097.
- William P. Jencks (1987). Catalysis in Chemistry and Enzymology. Dover Publications. ISBN 0486654605.
Spoljašnje veze[уреди | уреди извор]
- Long-chain-fatty-acyl-CoA+reductase на US National Library of Medicine Medical Subject Headings (MeSH)
