Endotelin konvertujući enzim 1
| Endotelin konvertujući enzim 1 | |||||||||
|---|---|---|---|---|---|---|---|---|---|
| Identifikatori | |||||||||
| EC broj | 3.4.24.71 | ||||||||
| CAS broj | 138238-81-0 | ||||||||
| Baze podataka | |||||||||
| IntEnz | IntEnz pregled | ||||||||
| BRENDA | BRENDA pristup | ||||||||
| ExPASy | NiceZyme pregled | ||||||||
| KEGG | KEGG pristup | ||||||||
| MetaCyc | metabolički put | ||||||||
| PRIAM | profil | ||||||||
| Strukture PBP | RCSB PDB PDBe PDBj PDBsum | ||||||||
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Endotelin konvertujući enzim 1 (EC 3.4.24.71, endotelin-konvertujući enzim, ECE-1) je enzim.[1][2][3] Ovaj enzim katalizuje sledeću hemijsku reakciju
- Hidroliza -Trp21-Val- veze u velikom endotelinu radi formiranja endotelina 1
Ova metaloendopeptidaza pripada familiji M13 (neprilizinskoj familiji).
Reference
[уреди | уреди извор]- ^ Takahashi, M., Matsushita, Y., Iijima, Y. and Tanzawa, K. (1993). „Purification and characterization of endothelin-converting enzyme from rat lung”. J. Biol. Chem. 268: 21394—21398. PMID 8407980.
- ^ Shimada, K., Takahashi, M. and Tanzawa, K. (1994). „Cloning and functional expression of endothelin-converting enzyme from rat endothelial cells”. J. Biol. Chem. 269: 18275—18278. PMID 8034569.
- ^ Xu, D., Emoto, N., Giaid, A., Slaughter, C., Kaw, S., DeWit, D. and Yanagisawa, M. (1994). „ECE-1: A membrane-bound metalloprotease that catalyzes the proteolytic activation of big endothelin-1”. Cell. 78: 473—485. PMID 8062389.
Literatura
[уреди | уреди извор]- Nicholas C. Price; Lewis Stevens (1999). Fundamentals of Enzymology: The Cell and Molecular Biology of Catalytic Proteins (Third изд.). USA: Oxford University Press. ISBN 019850229X.
- Eric J. Toone (2006). Advances in Enzymology and Related Areas of Molecular Biology, Protein Evolution (Volume 75 изд.). Wiley-Interscience. ISBN 0471205036.
- Branden C; Tooze J. Introduction to Protein Structure. New York, NY: Garland Publishing. ISBN 0-8153-2305-0.
- Irwin H. Segel. Enzyme Kinetics: Behavior and Analysis of Rapid Equilibrium and Steady-State Enzyme Systems (Book 44 изд.). Wiley Classics Library. ISBN 0471303097.
- William P. Jencks (1987). Catalysis in Chemistry and Enzymology. Dover Publications. ISBN 0486654605.
Spoljašnje veze
[уреди | уреди извор]- Endothelin-converting+enzyme+1 на US National Library of Medicine Medical Subject Headings (MeSH)
