FMN reduktaza (NADH)
| FMN reduktaza (NADH) | |||||||||
|---|---|---|---|---|---|---|---|---|---|
| Identifikatori | |||||||||
| EC broj | 1.5.1.42 | ||||||||
| Baze podataka | |||||||||
| IntEnz | IntEnz pregled | ||||||||
| BRENDA | BRENDA pristup | ||||||||
| ExPASy | NiceZyme pregled | ||||||||
| KEGG | KEGG pristup | ||||||||
| MetaCyc | metabolički put | ||||||||
| PRIAM | profil | ||||||||
| Strukture PBP | RCSB PDB PDBe PDBj PDBsum | ||||||||
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FMN reduktaza (NADH) (EC 1.5.1.42, NADH-FMN reduktaza, NADH-zavisna FMN reduktaza, NADH:FMN oksidoreduktaza, NADH:flavin oksidoreduktaza) je enzim sa sistematskim imenom FMNH2:NAD+ oksidoreduktaza.[1][2][3][4] Ovaj enzim katalizuje sledeću hemijsku reakciju
- FMNH2 + NAD+ FMN + NADH + H+
Ova enzim često formira dvokomponentni sistem sa monooksigenazama. Za razliku od enzima EC 1.5.1.38, FMN reduktaze (NADPH), i EC 1.5.1.39, FMN reduktaze [NAD(P)H], ovaj enzim ima jaku preferenciju za NADH u odnosu na NADPH.
Reference[уреди | уреди извор]
- ^ Duane, W. & Hastings, J.W. (1975). „Flavin mononucleotide reductase of luminous bacteria”. Mol. Cell. Biochem. 6: 53—64. PMID 47604.
- ^ Gerlo, E. & Charlier, J. (1975). „Identification of NADH-specific and NADPH-specific FMN reductases in Beneckea harveyi”. Eur. J. Biochem. 57: 461—467. PMID 1175652.
- ^ Uetz, T., Schneider, R., Snozzi, M. and Egli, T. (1992). „Purification and characterization of a two-component monooxygenase that hydroxylates nitrilotriacetate from "Chelatobacter" strain ATCC 29600”. J. Bacteriol. 174: 1179—1188. PMID 1735711.
- ^ Izumoto, Y., Mori, T. and Yamamoto, K. (1994). „Cloning and nucleotide sequence of the gene for NADH:FMN oxidoreductase from Vibrio harveyi”. Biochim. Biophys. Acta. 1185: 243—246. PMID 8167139.
Literatura[уреди | уреди извор]
- Nicholas C. Price; Lewis Stevens (1999). Fundamentals of Enzymology: The Cell and Molecular Biology of Catalytic Proteins (Third изд.). USA: Oxford University Press. ISBN 019850229X.
- Eric J. Toone (2006). Advances in Enzymology and Related Areas of Molecular Biology, Protein Evolution (Volume 75 изд.). Wiley-Interscience. ISBN 0471205036.
- Branden C; Tooze J. Introduction to Protein Structure. New York, NY: Garland Publishing. ISBN 0-8153-2305-0.
- Irwin H. Segel. Enzyme Kinetics: Behavior and Analysis of Rapid Equilibrium and Steady-State Enzyme Systems (Book 44 изд.). Wiley Classics Library. ISBN 0471303097.
- William P. Jencks (1987). Catalysis in Chemistry and Enzymology. Dover Publications. ISBN 0486654605.
Spoljašnje veze[уреди | уреди извор]
- FMN+reductase+(NADH) на US National Library of Medicine Medical Subject Headings (MeSH)
