FMN reduktaza (NADPH)
| FMN reduktaza (NADPH) | |||||||||
|---|---|---|---|---|---|---|---|---|---|
| Identifikatori | |||||||||
| EC broj | 1.5.1.38 | ||||||||
| Baze podataka | |||||||||
| IntEnz | IntEnz pregled | ||||||||
| BRENDA | BRENDA pristup | ||||||||
| ExPASy | NiceZyme pregled | ||||||||
| KEGG | KEGG pristup | ||||||||
| MetaCyc | metabolički put | ||||||||
| PRIAM | profil | ||||||||
| Strukture PBP | RCSB PDB PDBe PDBj PDBsum | ||||||||
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FMN reduktaza (NADPH) (EC 1.5.1.38, FRP, flavinska reduktaza P, SsuE) je enzim sa sistematskim imenom FMNH2:NADP+ oksidoreduktaza.[1][2][3][4][5][6][7][8] Ovaj enzim katalizuje sledeću hemijsku reakciju
- FMNH2 + NADP+ FMN + NADPH + H+
Enzimi iz bioluminescentih bakterija sadrže FMN, za razliku od enzima iz Escherichia coli.
Reference[уреди | уреди извор]
- ^ Gerlo, E. & Charlier, J. (1975). „Identification of NADH-specific and NADPH-specific FMN reductases in Beneckea harveyi”. Eur. J. Biochem. 57: 461—467. PMID 1175652.
- ^ Jablonski, E. & DeLuca, M. (1977). „Purification and properties of the NADH and NADPH specific FMN oxidoreductases from Beneckea harveyi”. Biochemistry. 16: 2932—2936. PMID 880288.
- ^ Jablonski, E. & DeLuca, M. (1978). „Studies of the control of luminescence in Beneckea harveyi: properties of the NADH and NADPH:FMN oxidoreductases”. Biochemistry. 17: 672—678. PMID 23827.
- ^ Lei, B., Liu, M., Huang, S. and Tu, S.C. (1994). „Vibrio harveyi NADPH-flavin oxidoreductase: cloning, sequencing and overexpression of the gene and purification and characterization of the cloned enzyme”. J. Bacteriol. 176: 3552—3558. PMID 8206832.
- ^ Tanner, J.J., Lei, B., Tu, S.C. and Krause, K.L. (1996). „Flavin reductase P: structure of a dimeric enzyme that reduces flavin”. Biochemistry. 35: 13531—13539. PMID 8885832.
- ^ Liu, M., Lei, B., Ding, Q., Lee, J.C. and Tu, S.C. (1997). „Vibrio harveyi NADPH:FMN oxidoreductase: preparation and characterization of the apoenzyme and monomer-dimer equilibrium”. Arch. Biochem. Biophys. 337: 89—95. PMID 8990272.
- ^ Lei, B. & Tu, S.C. (1998). „Mechanism of reduced flavin transfer from Vibrio harveyi NADPH-FMN oxidoreductase to luciferase”. Biochemistry. 37: 14623—14629. PMID 9772191.
- ^ Eichhorn, E., van der Ploeg, J.R. and Leisinger, T. (1999). „Characterization of a two-component alkanesulfonate monooxygenase from Escherichia coli”. J. Biol. Chem. 274: 26639—26646. PMID 10480865.
Literatura[уреди | уреди извор]
- Nicholas C. Price; Lewis Stevens (1999). Fundamentals of Enzymology: The Cell and Molecular Biology of Catalytic Proteins (Third изд.). USA: Oxford University Press. ISBN 019850229X.
- Eric J. Toone (2006). Advances in Enzymology and Related Areas of Molecular Biology, Protein Evolution (Volume 75 изд.). Wiley-Interscience. ISBN 0471205036.
- Branden C; Tooze J. Introduction to Protein Structure. New York, NY: Garland Publishing. ISBN 0-8153-2305-0.
- Irwin H. Segel. Enzyme Kinetics: Behavior and Analysis of Rapid Equilibrium and Steady-State Enzyme Systems (Book 44 изд.). Wiley Classics Library. ISBN 0471303097.
Spoljašnje veze[уреди | уреди извор]
- FMN+reductase+(NADPH) на US National Library of Medicine Medical Subject Headings (MeSH)
