Mukrolizin
| Mukrolizin | |||||||||
|---|---|---|---|---|---|---|---|---|---|
| Identifikatori | |||||||||
| EC broj | 3.4.24.54 | ||||||||
| CAS broj | 85898-38-0 | ||||||||
| Baze podataka | |||||||||
| IntEnz | IntEnz pregled | ||||||||
| BRENDA | BRENDA pristup | ||||||||
| ExPASy | NiceZyme pregled | ||||||||
| KEGG | KEGG pristup | ||||||||
| MetaCyc | metabolički put | ||||||||
| PRIAM | profil | ||||||||
| Strukture PBP | RCSB PDB PDBe PDBj PDBsum | ||||||||
| |||||||||
Mukrolizin (EC 3.4.24.54, Trimeresurus metaloendopeptidaza A, mukrotoksin A) je enzim.[1][2] Ovaj enzim katalizuje sledeću hemijsku reakciju
- Razlaganje Ser9-His, His10-Leu, Ala14-Leu, Leu15-Tyr i Tyr16-Leu veza u lancu insulina B
Ova hemoragična i fibrinogenolitička endopeptidaza je prisutana u venumu zmije Trimeresurus mucrosquamatus.
Reference[уреди | уреди извор]
- ^ Sugihara, H., Moriura, M. and Nikai, T. (1983). „P'urification and properties of a lethal, hemorrhagic protein, "mucrotoxin A", from the venom of the Chinese habu snake (Trimeresurus mucrosquamatus)”. Toxicon. 21: 247—255. PMID 6857709.
- ^ Kishida, M., Nikai, T., Mori, N., Kohmura, S. and Sugihara, H. (1985). „Characterization of mucrotoxin A from the venom of Trimeresurus mucrosquamatus (the Chinese habu snake)”. Toxicon. 23: 637—645. PMID 3904081.
Literatura[уреди | уреди извор]
- Nicholas C. Price; Lewis Stevens (1999). Fundamentals of Enzymology: The Cell and Molecular Biology of Catalytic Proteins (Third изд.). USA: Oxford University Press. ISBN 019850229X.
- Eric J. Toone (2006). Advances in Enzymology and Related Areas of Molecular Biology, Protein Evolution (Volume 75 изд.). Wiley-Interscience. ISBN 0471205036.
- Branden C; Tooze J. Introduction to Protein Structure. New York, NY: Garland Publishing. ISBN 0-8153-2305-0.
- Irwin H. Segel. Enzyme Kinetics: Behavior and Analysis of Rapid Equilibrium and Steady-State Enzyme Systems (Book 44 изд.). Wiley Classics Library. ISBN 0471303097.
- William P. Jencks (1987). Catalysis in Chemistry and Enzymology. Dover Publications. ISBN 0486654605.
Spoljašnje veze[уреди | уреди извор]
- Mucrolysin на US National Library of Medicine Medical Subject Headings (MeSH)
