Peptidilna dipeptidaza B
(преусмерено са Peptidil-dipeptidaza B)
| Peptidilna dipeptidaza B | |||||||||
|---|---|---|---|---|---|---|---|---|---|
| Identifikatori | |||||||||
| EC broj | 3.4.15.4 | ||||||||
| CAS broj | 147014-93-5 | ||||||||
| Baze podataka | |||||||||
| IntEnz | IntEnz pregled | ||||||||
| BRENDA | BRENDA pristup | ||||||||
| ExPASy | NiceZyme pregled | ||||||||
| KEGG | KEGG pristup | ||||||||
| MetaCyc | metabolički put | ||||||||
| PRIAM | profil | ||||||||
| Strukture PBP | RCSB PDB PDBe PDBj PDBsum | ||||||||
| |||||||||
Peptidilna dipeptidaza B (EC 3.4.15.4, dipeptidilna karboksihidrolaza, atriopeptinska konvertaza, atrijalna di-(tri)peptidilna karboksihidrolaza, peptidilnadipeptidaza B, atrijalna dipeptidilna karboksihidrolaza, atrijalna peptidna konvertaza) je enzim.[1][2][3][4] Ovaj enzim katalizuje sledeću hemijsku reakciju
- Odvajanje C-terminalnog dipeptida ili u retkim slučajevima tripeptida
Ova membranska, cinkova metalopeptidaza je prisutan u sisarskim atrijalnim miocitima.
Reference[уреди | уреди извор]
- ^ Harris, R.B. & Wilson, I.B. (1984). „Atrial tissue contains a metallo dipeptidyl carboxyhydrolase not present in ventricular tissue: partial purification and characterization”. Arch. Biochem. Biophys. 233: 667—675. PMID 6385859.
- ^ Harris, R.B. & Wilson, I.B. (1985). „Conversion of atriopeptin II to atriopeptin I by atrial dipeptidyl carboxy hydrolase”. Peptides (Fayetteville). 6: 393—396. PMID 2999723.
- ^ Soler, D.F. & Harris, R.B. (1988). „Continuous fluorogenic substrates for atrial dipeptidyl carboxyhydrolase. Importance of Ser in the P1 position”. Int. J. Peptide Protein Res. 32: 35—40. PMID 3146555.
- ^ Soler, D.F. & Harris, R.B. (1989). „Atrial dipeptidyl carboxyhydrolase is a zinc-metallo proteinase which possesses tripeptidyl carboxyhydrolase activity”. Peptides (Fayetteville). 10: 63—68. PMID 2501770.
Literatura[уреди | уреди извор]
- Nicholas C. Price; Lewis Stevens (1999). Fundamentals of Enzymology: The Cell and Molecular Biology of Catalytic Proteins (Third изд.). USA: Oxford University Press. ISBN 019850229X.
- Eric J. Toone (2006). Advances in Enzymology and Related Areas of Molecular Biology, Protein Evolution (Volume 75 изд.). Wiley-Interscience. ISBN 0471205036.
- Branden C; Tooze J. Introduction to Protein Structure. New York, NY: Garland Publishing. ISBN 0-8153-2305-0.
- Irwin H. Segel. Enzyme Kinetics: Behavior and Analysis of Rapid Equilibrium and Steady-State Enzyme Systems (Book 44 изд.). Wiley Classics Library. ISBN 0471303097.
- William P. Jencks (1987). Catalysis in Chemistry and Enzymology. Dover Publications. ISBN 0486654605.
Spoljašnje veze[уреди | уреди извор]
- Peptidyl-dipeptidase+B на US National Library of Medicine Medical Subject Headings (MeSH)
