Prepilinska peptidaza
| Prepilinska peptidaza | |||||||||
|---|---|---|---|---|---|---|---|---|---|
| Identifikatori | |||||||||
| EC broj | 3.4.23.43 | ||||||||
| CAS broj | 202833-59-8 | ||||||||
| Baze podataka | |||||||||
| IntEnz | IntEnz pregled | ||||||||
| BRENDA | BRENDA pristup | ||||||||
| ExPASy | NiceZyme pregled | ||||||||
| KEGG | KEGG pristup | ||||||||
| MetaCyc | metabolički put | ||||||||
| PRIAM | profil | ||||||||
| Strukture PBP | RCSB PDB PDBe PDBj PDBsum | ||||||||
| |||||||||
Prepilinska peptidaza (EC 3.4.23.43) je enzim.[1][2] Ovaj enzim katalizuje sledeću hemijsku reakciju
- Tipično dolazi do razlaganja -Gly-Phe- veze čime se oslobađa N-terminalni, bazni peptid sa 5-8 ostataka sa tipa IV prepilina, i zatim se N-metiliše nova N-terminal amino grupa, pri čemu je metilni donor S-adenozil-L-metionin
Ovaj enzim je prisutan u mnogim vrstama bakterije Carry pili.
Reference[уреди | уреди извор]
- ^ Lory, S. & Strom, M.S. (1997). „Structure-function relationship of type-IV prepilin peptidase of Pseudomonas aeruginosa - A review”. Gene. 192: 117—121. PMID 9224881.
- ^ LaPointe, C.F. & Taylor, R.K. (2000). „The type 4 prepilin peptidases comprise a novel family of aspartic acid proteases”. J. Biol. Chem. 275: 1502—1510. PMID 10625704.
Literatura[уреди | уреди извор]
- Nicholas C. Price; Lewis Stevens (1999). Fundamentals of Enzymology: The Cell and Molecular Biology of Catalytic Proteins (Third изд.). USA: Oxford University Press. ISBN 019850229X.
- Eric J. Toone (2006). Advances in Enzymology and Related Areas of Molecular Biology, Protein Evolution (Volume 75 изд.). Wiley-Interscience. ISBN 0471205036.
- Branden C; Tooze J. Introduction to Protein Structure. New York, NY: Garland Publishing. ISBN 0-8153-2305-0.
- Irwin H. Segel. Enzyme Kinetics: Behavior and Analysis of Rapid Equilibrium and Steady-State Enzyme Systems (Book 44 изд.). Wiley Classics Library. ISBN 0471303097.
- William P. Jencks (1987). Catalysis in Chemistry and Enzymology. Dover Publications. ISBN 0486654605.
Spoljašnje veze[уреди | уреди извор]
- Prepilin+peptidase на US National Library of Medicine Medical Subject Headings (MeSH)
