TRNK (adenin22-N1)-metiltransferaza
| TRNK (adenin22-N1)-metiltransferaza | |||||||||
|---|---|---|---|---|---|---|---|---|---|
| Identifikatori | |||||||||
| EC broj | 2.1.1.217 | ||||||||
| Baze podataka | |||||||||
| IntEnz | IntEnz pregled | ||||||||
| BRENDA | BRENDA pristup | ||||||||
| ExPASy | NiceZyme pregled | ||||||||
| KEGG | KEGG pristup | ||||||||
| MetaCyc | metabolički put | ||||||||
| PRIAM | profil | ||||||||
| Strukture PBP | RCSB PDB PDBe PDBj PDBsum | ||||||||
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TRNK (adenin22-N1)-metiltransferaza (EC 2.1.1.217, TrmK, YqfN, Sp1610 (gen), tRNK: m1A22 metiltransferaza) je enzim sa sistematskim imenom S-adenozil-L-metionin:tRNK (adenin22-N1)-metiltransferaza.[1][2] Ovaj enzim katalizuje sledeću hemijsku reakciju
- S-adenozil-L-metionin + adenin22 u tRNK S-adenozil-L-homocistein + N1-metiladenin22 u tRNK
Ovaj enzim specifično metiluje adenin22 u tRNK.
Reference[уреди | уреди извор]
- ^ Ta, H.M. & Kim, K.K. (2010). „Crystal structure of Streptococcus pneumoniae Sp1610, a putative tRNA methyltransferase, in complex with S-adenosyl-L-methionine”. Protein Sci. 19: 617—624. PMID 20052680.
- ^ Roovers, M., Kaminska, K.H., Tkaczuk, K.L., Gigot, D., Droogmans, L. and Bujnicki, J.M. (2008). „The YqfN protein of Bacillus subtilis is the tRNA: m1A22 methyltransferase (TrmK)”. Nucleic Acids Res. 36: 3252—3262. PMID 18420655.
Literatura[уреди | уреди извор]
- Nicholas C. Price; Lewis Stevens (1999). Fundamentals of Enzymology: The Cell and Molecular Biology of Catalytic Proteins (Third изд.). USA: Oxford University Press. ISBN 019850229X.
- Eric J. Toone (2006). Advances in Enzymology and Related Areas of Molecular Biology, Protein Evolution (Volume 75 изд.). Wiley-Interscience. ISBN 0471205036.
- Branden C; Tooze J. Introduction to Protein Structure. New York, NY: Garland Publishing. ISBN 0-8153-2305-0.
- Irwin H. Segel. Enzyme Kinetics: Behavior and Analysis of Rapid Equilibrium and Steady-State Enzyme Systems (Book 44 изд.). Wiley Classics Library. ISBN 0471303097.
- William P. Jencks (1987). Catalysis in Chemistry and Enzymology. Dover Publications. ISBN 0486654605.
Spoljašnje veze[уреди | уреди извор]
- TRNA+(adenine22-N1)-methyltransferase на US National Library of Medicine Medical Subject Headings (MeSH)
