Пиролин-5-карбоксилат редуктаза
| Pirolin-5-karboksilat reduktaza | |||||||||
|---|---|---|---|---|---|---|---|---|---|
 Pirolin-5-karboksilat reduktaza dekamer, Human | |||||||||
| Identifikatori | |||||||||
| EC broj | 1.5.1.2 | ||||||||
| CAS broj | 9029-17-8 | ||||||||
| Baze podataka | |||||||||
| IntEnz | IntEnz pregled | ||||||||
| BRENDA | BRENDA pristup | ||||||||
| ExPASy | NiceZyme pregled | ||||||||
| KEGG | KEGG pristup | ||||||||
| MetaCyc | metabolički put | ||||||||
| PRIAM | profil | ||||||||
| Strukture PBP | RCSB PDB PDBe PDBj PDBsum | ||||||||
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Pirolin-5-karboksilat reduktaza (EC 1.5.1.2, prolinska oksidaza, L-prolinska oksidaza, 1-pirolidin-5-karboksilat reduktaza, NADPH-L-Delta1-pirolidin karboksilna kiselina reduktaza, L-prolin-NAD(P)+ 5-oksidoreduktaza) je enzim sa sistematskim imenom L-prolin:NAD(P)+ 5-oksidoreduktaza.[1][2][3][4] Ovaj enzim katalizuje sledeću hemijsku reakciju
- L-prolin + NAD(P)+ 1-pirolidin-5-karboksilat + NAD(P)H + H+
Ovaj enzim takođe redukuje 1-pirolidin-3-hidroksi-5-karboksilat do L-hidroksiprolina.
Reference[уреди | уреди извор]
- ^ Adams, E. & Goldstone, A. (1960). „Hydroxyproline metabolism. III. Enzymatic synthesis of hydroxyproline from Δ1-pyrroline-3-hydroxy-5-carboxylate”. J. Biol. Chem. 235: 3499—3503. PMID 13681369.
- ^ Meister, A., Radhakrishnan, A.N. and Buckley, S.D. (1957). „Enzymatic synthesis of L-pipecolic acid and L-proline”. J. Biol. Chem. 229: 789—800. PMID 13502341.
- ^ Smith, M.E. & Greenberg, D.M. (1956). „Characterization of an enzyme reducing pyrroline-5-carboxylate to proline”. Nature (Lond.). 177: 1130—1130. PMID 13334497.
- ^ Yura, T. & Vogel, H.J. (1959). „Pyrroline-5-carboxylate reductase of Neurospora crassa: partial purification and some properties”. J. Biol. Chem. 234: 335—338. PMID 13630905.
Literatura[уреди | уреди извор]
- Nicholas C. Price; Lewis Stevens (1999). Fundamentals of Enzymology: The Cell and Molecular Biology of Catalytic Proteins (Third изд.). USA: Oxford University Press. ISBN 019850229X.
- Eric J. Toone (2006). Advances in Enzymology and Related Areas of Molecular Biology, Protein Evolution (Volume 75 изд.). Wiley-Interscience. ISBN 0471205036.
- Branden C; Tooze J. Introduction to Protein Structure. New York, NY: Garland Publishing. ISBN 0-8153-2305-0.
- Irwin H. Segel. Enzyme Kinetics: Behavior and Analysis of Rapid Equilibrium and Steady-State Enzyme Systems (Book 44 изд.). Wiley Classics Library. ISBN 0471303097.
Spoljašnje veze[уреди | уреди извор]
- Pyrroline-5-carboxylate+reductase на US National Library of Medicine Medical Subject Headings (MeSH)
