3-Heksuloza-6-fosfatna sintaza
| 3-Heksuloza-6-fosfatna sintaza | |||||||||
|---|---|---|---|---|---|---|---|---|---|
| Identifikatori | |||||||||
| EC broj | 4.1.2.43 | ||||||||
| Baze podataka | |||||||||
| IntEnz | IntEnz pregled | ||||||||
| BRENDA | BRENDA pristup | ||||||||
| ExPASy | NiceZyme pregled | ||||||||
| KEGG | KEGG pristup | ||||||||
| MetaCyc | metabolički put | ||||||||
| PRIAM | profil | ||||||||
| Strukture PBP | RCSB PDB PDBe PDBj PDBsum | ||||||||
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3-Heksuloza-6-fosfatna sintaza (EC 4.1.2.43, D-arabino-3-heksuloza 6-fosfat formaldehid-lijaza, 3-heksulozafosfat sintaza, 3-heksuloza fosfat sintaza, HPS) je enzim sa sistematskim imenom D-arabino-heks-3-uloza-6-fosfat formaldehid-lijaza (formira D-ribuloza-5-fosfat).[1][2][3][4][5][6][7] Ovaj enzim katalizuje sledeću hemijsku reakciju
- D-arabino-heks-3-uloza 6-fosfat D-ribuloza 5-fosfat + formaldehid
Za maksimalno dejstvo ovog enzima je neophodan jon Mg2+ ili Mn2+.
Reference
[уреди | уреди извор]- ^ Ferenci, T., Strøm, T. and Quayle, J.R. (1974). „Purification and properties of 3-hexulose phosphate synthase and phospho-3-hexuloisomerase from Methylococcus capsulatus”. Biochem. J. 144: 477—486. PMID 4219834.
- ^ Kato, N., Ohashi, H., Tani, Y. and Ogata, K. (1978). „3-Hexulosephosphate synthase from Methylomonas aminofaciens 77a. Purification, properties and kinetics”. Biochim. Biophys. Acta. 523: 236—244. PMID 564713.
- ^ Yanase, H., Ikeyama, K., Mitsui, R., Ra, S., Kita, K., Sakai, Y. and Kato, N. (1996). „Cloning and sequence analysis of the gene encoding 3-hexulose-6-phosphate synthase from the methylotrophic bacterium, Methylomonas aminofaciens 77a, and its expression in Escherichia coli”. FEMS Microbiol. Lett. 135: 201—205. PMID 8595859.
- ^ Yurimoto, H., Kato, N. and Sakai, Y. (2005). „Assimilation, dissimilation, and detoxification of formaldehyde, a central metabolic intermediate of methylotrophic metabolism”. Chem. Rec. 5: 367—375. PMID 16278835.
- ^ Kato, N., Yurimoto, H. and Thauer, R.K. (2006). „The physiological role of the ribulose monophosphate pathway in bacteria and archaea”. Biosci. Biotechnol. Biochem. 70: 10—21. PMID 16428816.
- ^ Orita, I., Yurimoto, H., Hirai, R., Kawarabayasi, Y., Sakai, Y. and Kato, N. (2005). „The archaeon Pyrococcus horikoshii possesses a bifunctional enzyme for formaldehyde fixation via the ribulose monophosphate pathway”. J. Bacteriol. 187: 3636—3642. PMID 15901685.
- ^ Kato, N., Miyamoto, N., Shimao, M. and Sakazawa, C. (1988). „3-Hexulose phosphate pynthase from a new facultative methylotroph, Mycobacterium gastri MB19”. Agric. Biol. Chem. 52: 2659—2661.
Literatura
[уреди | уреди извор]- Nicholas C. Price; Lewis Stevens (1999). Fundamentals of Enzymology: The Cell and Molecular Biology of Catalytic Proteins (Third изд.). USA: Oxford University Press. ISBN 019850229X.
- Eric J. Toone (2006). Advances in Enzymology and Related Areas of Molecular Biology, Protein Evolution (Volume 75 изд.). Wiley-Interscience. ISBN 0471205036.
- Branden C; Tooze J. Introduction to Protein Structure. New York, NY: Garland Publishing. ISBN 0-8153-2305-0.
- Irwin H. Segel. Enzyme Kinetics: Behavior and Analysis of Rapid Equilibrium and Steady-State Enzyme Systems (Book 44 изд.). Wiley Classics Library. ISBN 0471303097.
Spoljašnje veze
[уреди | уреди извор]- 3-hexulose-6-phosphate+synthase на US National Library of Medicine Medical Subject Headings (MeSH)
