Kinaza receptora za lipoprotein niske gustine
| Kinaza receptora za lipoprotein niske gustine | |||||||||
|---|---|---|---|---|---|---|---|---|---|
| Identifikatori | |||||||||
| EC broj | 2.7.11.29 | ||||||||
| CAS broj | 107445-00-1 | ||||||||
| Baze podataka | |||||||||
| IntEnz | IntEnz pregled | ||||||||
| BRENDA | BRENDA pristup | ||||||||
| ExPASy | NiceZyme pregled | ||||||||
| KEGG | KEGG pristup | ||||||||
| MetaCyc | metabolički put | ||||||||
| PRIAM | profil | ||||||||
| Strukture PBP | RCSB PDB PDBe PDBj PDBsum | ||||||||
| |||||||||
Kinaza receptora za lipoprotein niske gustine (EC 2.7.11.29, ATP:lipoprotein niske gustine L-serin O-fosfotransferaza, LDL receptorska kinaza, (lipoprotein niske gustine) kinaza, kinaza lipoproteina niske gustine, receptorska kinaza lipoproteina niske gustine (fosforilacija), STK7) je enzim sa sistematskim imenom ATP:(receptor lipoproteina niske gustine)-L-serin O-fosfotransferaza.[1][2] Ovaj enzim katalizuje sledeću hemijsku reakciju
- ATP + [receptor lipoprotein niske gustine]-L-serin ADP + [receptor lipoprotein niske gustine]-O-fosfo-L-serin
Ovaj enzim fosforiliše zadnji serinski ostatak (Ser-833) u citoplazmičnom domenu receptora lipoproteina niske gustine iz goveđeg adrenalnog korteksa.
Reference
[уреди | уреди извор]- ^ Kishimoto, A., Brown, M.S., Slaughter, C.A. and Goldstein, J.L. (1987). „Phosphorylation of serine 833 in cytoplasmic domain of low density lipoprotein receptor by a high molecular weight enzyme resembling casein kinase II”. J. Biol. Chem. 262: 1344—1351. PMID 3100530.
- ^ Kishimoto, A., Goldstein, J.L. and Brown, M.S. (1987). „Purification of catalytic subunit of low density lipoprotein receptor kinase and identification of heat-stable activator protein”. J. Biol. Chem. 262: 9367—9373. PMID 3597414.
Literatura
[уреди | уреди извор]- Nicholas C. Price; Lewis Stevens (1999). Fundamentals of Enzymology: The Cell and Molecular Biology of Catalytic Proteins (Third изд.). USA: Oxford University Press. ISBN 019850229X.
- Eric J. Toone (2006). Advances in Enzymology and Related Areas of Molecular Biology, Protein Evolution (Volume 75 изд.). Wiley-Interscience. ISBN 0471205036.
- Branden C; Tooze J. Introduction to Protein Structure. New York, NY: Garland Publishing. ISBN 0-8153-2305-0.
- Irwin H. Segel. Enzyme Kinetics: Behavior and Analysis of Rapid Equilibrium and Steady-State Enzyme Systems (Book 44 изд.). Wiley Classics Library. ISBN 0471303097.
Spoljašnje veze
[уреди | уреди извор]- Low-density-lipoprotein+receptor+kinase на US National Library of Medicine Medical Subject Headings (MeSH)
