Aklidinijum bromid
 |
| Klinički podaci |
| Prodajno ime |
Bretaris Genuair, Eklira Genuair, Tudorza Pressair |
| Drugs.com |
bromide.html Monografija |
| Način primene |
Respiratorno (inhalacija) |
| Farmakokinetički podaci |
| Poluvreme eliminacije |
2,4 minuta |
| Izlučivanje |
Renalno |
|
| Identifikatori |
| CAS broj |
320345-99-1  Y |
| ATC kod |
R03BB05 (WHO) |
| PubChem |
CID 11519741 |
| DrugBank |
DB08897 Y |
| ChemSpider |
9694529 Y |
| ChEBI |
CHEBI:65344 Y |
| ChEMBL |
CHEMBL551466 Y |
| Hemijski podaci |
| Formula |
C26H30BrNO4S2 |
| Molarna masa |
564,555 |
-
[Br-].OC(C(=O)OC1C[N+]2(CCCOC3=CC=CC=C3)CCC1CC2)(C1=CC=CS1)C1=CC=CS1
|
-
InChI=1/C26H30NO4S2.BrH/c28-25(26(29,23-9-4-17-32-23)24-10-5-18-33-24)31-22-19-27(14-11-20(22)12-15-27)13-6-16-30-21-7-2-1-3-8-21;/h1-5,7-10,17-18,20,22,29H,6,11-16,19H2;1H/q+1;/p-1 Y
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Key:XLAKJQPTOJHYDR-UHFFFAOYNA-M Y
|
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Aklidinijum bromid je organsko jedinjenje, koje sadrži 26 atoma ugljenika i ima molekulsku masu od 564,555 Da.[1][2][3][4][5]
Reference[уреди]
- ↑ Reid DJ, Pham NT: Emerging Therapeutic Options for the Management of COPD. Clin Med Insights Circ Respir Pulm Med. 2013 Apr 9;7:7-15. doi: 10.4137/CCRPM.S8140. Print 2013. PMID 23641160
- ↑ Cazzola M, Page CP, Matera MG: Aclidinium bromide for the treatment of chronic obstructive pulmonary disease. Expert Opin Pharmacother. 2013 Jun;14(9):1205-14. doi: 10.1517/14656566.2013.789021. Epub 2013 Apr 9. PMID 23566013
- ↑ Jones P: Aclidinium bromide twice daily for the treatment of chronic obstructive pulmonary disease: a review. Adv Ther. 2013 Apr;30(4):354-68. doi: 10.1007/s12325-013-0019-2. Epub 2013 Apr 2. PMID 23553509
- ↑ Knox C, Law V, Jewison T, Liu P, Ly S, Frolkis A, Pon A, Banco K, Mak C, Neveu V, Djoumbou Y, Eisner R, Guo AC, Wishart DS (2011). „DrugBank 3.0: a comprehensive resource for omics research on drugs”. Nucleic Acids Res. 39 (Database issue): D1035—41. PMC 3013709
. PMID 21059682. doi:10.1093/nar/gkq1126.
- ↑ David S. Wishart; Craig Knox; An Chi Guo; Dean Cheng; Savita Shrivastava; Dan Tzur; Bijaya Gautam; Murtaza Hassanali (2008). „DrugBank: a knowledgebase for drugs, drug actions and drug targets”. Nucleic acids research. 36 (Database issue): D901—6. PMC 2238889 . PMID 18048412. doi:10.1093/nar/gkm958.
- ↑ Ghose, A.K.; Viswanadhan V.N. & Wendoloski, J.J. (1998). „Prediction of Hydrophobic (Lipophilic) Properties of Small Organic Molecules Using Fragment Methods: An Analysis of AlogP and CLogP Methods”. J. Phys. Chem. A. 102: 3762—3772. doi:10.1021/jp980230o.
- ↑ Tetko IV, Tanchuk VY, Kasheva TN, Villa AE (2001). „Estimation of Aqueous Solubility of Chemical Compounds Using E-State Indices”. Chem Inf. Comput. Sci. 41: 1488—1493. PMID 11749573. doi:10.1021/ci000392t.
- ↑ Ertl P.; Rohde B.; Selzer P. (2000). „Fast calculation of molecular polar surface area as a sum of fragment based contributions and its application to the prediction of drug transport properties”. J. Med. Chem. 43: 3714—3717. PMID 11020286. doi:10.1021/jm000942e.
Literatura[уреди]
Spoljašnje veze[уреди]
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