KoA-glutation reduktaza
(преусмерено са EC 1.8.1.10)
| KoA-glutation reduktaza | |||||||||
|---|---|---|---|---|---|---|---|---|---|
| Identifikatori | |||||||||
| EC broj | 1.8.1.10 | ||||||||
| CAS broj | 37256-33-0 | ||||||||
| Baze podataka | |||||||||
| IntEnz | IntEnz pregled | ||||||||
| BRENDA | BRENDA pristup | ||||||||
| ExPASy | NiceZyme pregled | ||||||||
| KEGG | KEGG pristup | ||||||||
| MetaCyc | metabolički put | ||||||||
| PRIAM | profil | ||||||||
| Strukture PBP | RCSB PDB PDBe PDBj PDBsum | ||||||||
| |||||||||
KoA-glutation reduktaza (EC 1.8.1.10, koenzim A glutation disulfidna reduktaza, NADPH-zavisna koenzim A-SS-glutationska reduktaza, koenzim A disulfid-glutationska reduktaza, NADPH:KoA-glutationska oksidoreduktaza) je enzim sa sistematskim imenom glutation:NADP+ oksidoreduktaza (KoA-acilacija).[1][2][3] Ovaj enzim katalizuje sledeću hemijsku reakciju
- KoA + glutation + NADP+ KoA-glutation + NADPH + H+
Ovaj enzim je flavoprotein. Supstrat je mešoviti disulfid.
Reference[уреди | уреди извор]
- ^ Ondarza, R.N., Abney, R. and López-Colomé, A.M. (1969). „Characterization of a NADPH-dependent coenzyme A-SS-glutathione reductase from yeast”. Biochim. Biophys. Acta. 191: 239—248. PMID 4390951.
- ^ Ondarza, R.N., Escamilla, E., Gutierrez, J. and De la Chica, G. (1974). „CoAS-Sglutathione and GSSG reductases from rat liver. Two disulfide oxidoreductase activities in one protein entity”. Biochim. Biophys. Acta. 341: 162—171. PMID 4151341.
- ^ Carlberg, I. & Mannervik, B. (1977). „Purification by affinity chromatography of yeast glutathione reductase, the enzyme responsible for the NADPH-dependent reduction of the mixed disulfide of coenzyme A and glutathione”. Biochim. Biophys. Acta. 484: 268—274. PMID 334266.
Literatura[уреди | уреди извор]
- Nicholas C. Price; Lewis Stevens (1999). Fundamentals of Enzymology: The Cell and Molecular Biology of Catalytic Proteins (Third изд.). USA: Oxford University Press. ISBN 019850229X.
- Eric J. Toone (2006). Advances in Enzymology and Related Areas of Molecular Biology, Protein Evolution (Volume 75 изд.). Wiley-Interscience. ISBN 0471205036.
- Branden C; Tooze J. Introduction to Protein Structure. New York, NY: Garland Publishing. ISBN 0-8153-2305-0.
- Irwin H. Segel. Enzyme Kinetics: Behavior and Analysis of Rapid Equilibrium and Steady-State Enzyme Systems (Book 44 изд.). Wiley Classics Library. ISBN 0471303097.
- William P. Jencks (1987). Catalysis in Chemistry and Enzymology. Dover Publications. ISBN 0486654605.
Spoljašnje veze[уреди | уреди извор]
- CoA-glutathione+reductase на US National Library of Medicine Medical Subject Headings (MeSH)
