Metionilna aminopeptidaza
| Metionilna aminopeptidaza | |||||||||
|---|---|---|---|---|---|---|---|---|---|
| Identifikatori | |||||||||
| EC broj | 3.4.11.18 | ||||||||
| CAS broj | 61229-81-0 | ||||||||
| Baze podataka | |||||||||
| IntEnz | IntEnz pregled | ||||||||
| BRENDA | BRENDA pristup | ||||||||
| ExPASy | NiceZyme pregled | ||||||||
| KEGG | KEGG pristup | ||||||||
| MetaCyc | metabolički put | ||||||||
| PRIAM | profil | ||||||||
| Strukture PBP | RCSB PDB PDBe PDBj PDBsum | ||||||||
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Metionilna aminopeptidaza (EC 3.4.11.18, metioninska aminopeptidaza, peptidaza M, L-metioninska aminopeptidaza, MAP) je enzim.[1][2][3][4][5] Ovaj enzim katalizuje sledeću hemijsku reakciju
- Oslobađanje N-terminalne aminokiseline, preferentno metionina, sa peptida i arilamida
Ovaj za membranu vezani enzim je prisutan kod prokariota i eukariota.
Reference[уреди | уреди извор]
- ^ Yoshida, A. & Lin, M. (1972). „NH2-terminal formylmethionine- and NH2-terminal methionine-cleaving enzymes in rabbits”. J. Biol. Chem. 247: 952—957. PMID 4110013.
- ^ Tsunasawa, S., Stewart, J.W. and Sherman, F. (1985). „Acylamino acid-releasing enzyme from rat liver”. J. Biol. Chem. 260: 5832—5391. PMID 2985590.
- ^ Freitas, J.O., Jr., Termignoni, C. and Guimaraes, J.A. (1985). „Methionine aminopeptidase associated with liver mitochondria and microsomes”. Int. J. Biochem. 17: 1285—1291. PMID 3937747.
- ^ Ben-Bassat, A., Bauer, K., Chang, S.-Y., Myambo, K., Boosman, A. and Chang, S. (1987). „Processing of the initiation methionine from proteins: properties of Escherichia coli methionine aminopeptidase and its gene structure”. J. Bacteriol. 169: 751—757. PMID 3027045.
- ^ Roderick, S.L. & Mathews, B.W. (1988). „Crystallization of methionine aminopeptidase from Escherichia coli”. J. Biol. Chem. 263: 16531—16531. PMID 89034132.
Literatura[уреди | уреди извор]
- Nicholas C. Price; Lewis Stevens (1999). Fundamentals of Enzymology: The Cell and Molecular Biology of Catalytic Proteins (Third изд.). USA: Oxford University Press. ISBN 019850229X.
- Eric J. Toone (2006). Advances in Enzymology and Related Areas of Molecular Biology, Protein Evolution (Volume 75 изд.). Wiley-Interscience. ISBN 0471205036.
- Branden C; Tooze J. Introduction to Protein Structure. New York, NY: Garland Publishing. ISBN 0-8153-2305-0.
- Irwin H. Segel. Enzyme Kinetics: Behavior and Analysis of Rapid Equilibrium and Steady-State Enzyme Systems (Book 44 изд.). Wiley Classics Library. ISBN 0471303097.
Spoljašnje veze[уреди | уреди извор]
- Methionyl+aminopeptidase на US National Library of Medicine Medical Subject Headings (MeSH)
