XYLT2

XYLT2
Identifikatori
Alijasi	XYLT2
Spoljašnji ID	OMIM: 608125 MGI: 2444797 HomoloGene: 23349 GeneCards: XYLT2
Genska lokacija (miš)
Hr.	Chromosome 11 (mouse)
Kraj	94,568,341 bp
Obrazac RNK izražavanja
	More reference expression data
Genska ontologija
Molecular function	• transferase activity; • acetylglucosaminyltransferase activity; • glycosyltransferase activity; • protein xylosyltransferase activity; • magnesium ion binding; • manganese ion binding; • metal ion binding;
Cellular component	• саставни део мембране; • Голџијев апарат; • endoplasmic reticulum membrane; • ендоплазматични ретикулум; • мембрана; • Golgi membrane; • ћелијски састојак; • ванћелијски простор; • ванћелијска област;
Biological process	• chondroitin sulfate biosynthetic process; • chondroitin sulfate proteoglycan biosynthetic process; • heparan sulfate proteoglycan biosynthetic process; • heparin biosynthetic process; • glycosaminoglycan biosynthetic process; • proteoglycan biosynthetic process; • glycosaminoglycan metabolic process;
	Sources:Amigo / QuickGO
Ortolozi
	64132
	217119
	ENSG00000015532
	ENSMUSG00000020868
	Q9H1B5
	Q9EPL0
	NM_022167
	NM_145828
	NP_071450
	NP_665827
	Wikidata
View/Edit Human	View/Edit Mouse

Ksiloziltransferaza 2 je enzim koji je kod ljudi kodiran genom XYLT2.^[4]^[5]

Reference[уреди | уреди извор]

^ ^а ^б ^в GRCm38: Ensembl release 89: ENSMUSG00000020868 - Ensembl, May 2017
^ „Human PubMed Reference:”. National Center for Biotechnology Information, U.S. National Library of Medicine.
^ „Mouse PubMed Reference:”. National Center for Biotechnology Information, U.S. National Library of Medicine.
^ Götting C, Kuhn J, Zahn R, Brinkmann T, Kleesiek K (децембар 2000). „Molecular cloning and expression of human UDP-d-Xylose:proteoglycan core protein beta-d-xylosyltransferase and its first isoform XT-II”. Journal of Molecular Biology. 304 (4): 517—28. PMID 11099377. doi:10.1006/jmbi.2000.4261.
^ „Entrez Gene: XYLT2 xylosyltransferase II”.

Literatura[уреди | уреди извор]

Götting C, Kuhn J, Brinkmann T, Kleesiek K (април 1998). „Xylosylation of alternatively spliced isoforms of Alzheimer APP by xylosyltransferase”. Journal of Protein Chemistry. 17 (3): 295—302. PMID 9588955. S2CID 39212266. doi:10.1023/A:1022549121672.
Götting C, Sollberg S, Kuhn J, Weilke C, Huerkamp C, Brinkmann T, Krieg T, Kleesiek K (јун 1999). „Serum xylosyltransferase: a new biochemical marker of the sclerotic process in systemic sclerosis”. The Journal of Investigative Dermatology. 112 (6): 919—24. PMID 10383739. doi:10.1046/j.1523-1747.1999.00590.x .
Kuhn J, Götting C, Schnölzer M, Kempf T, Brinkmann T, Kleesiek K (фебруар 2001). „First isolation of human UDP-D-xylose: proteoglycan core protein beta-D-xylosyltransferase secreted from cultured JAR choriocarcinoma cells”. The Journal of Biological Chemistry. 276 (7): 4940—7. PMID 11087729. doi:10.1074/jbc.M005111200 .
Götting C, Kuhn J, Brinkmann T, Kleesiek K (март 2002). „Xylosyltransferase activity in seminal plasma of infertile men”. Clinica Chimica Acta; International Journal of Clinical Chemistry. 317 (1–2): 199—202. PMID 11814476. doi:10.1016/S0009-8981(01)00793-8.
Schön S, Prante C, Müller S, Schöttler M, Tarnow L, Kuhn J, Kleesiek K, Götting C (октобар 2005). „Impact of polymorphisms in the genes encoding xylosyltransferase I and a homologue in type 1 diabetic patients with and without nephropathy”. Kidney International. 68 (4): 1483—90. PMID 16164625. doi:10.1111/j.1523-1755.2005.00561.x .
Schön S, Prante C, Bahr C, Kuhn J, Kleesiek K, Götting C (мај 2006). „Cloning and recombinant expression of active full-length xylosyltransferase I (XT-I) and characterization of subcellular localization of XT-I and XT-II”. The Journal of Biological Chemistry. 281 (20): 14224—31. PMID 16569644. doi:10.1074/jbc.M510690200 .
Voglmeir J, Voglauer R, Wilson IB (март 2007). „XT-II, the second isoform of human peptide-O-xylosyltransferase, displays enzymatic activity”. The Journal of Biological Chemistry. 282 (9): 5984—90. PMC 2850172 . PMID 17194707. doi:10.1074/jbc.M608087200 .

[refGRCm38Ensembl-1] а ^б ^в GRCm38: Ensembl release 89: ENSMUSG00000020868 - Ensembl, May 2017

[2] „Human PubMed Reference:”. National Center for Biotechnology Information, U.S. National Library of Medicine.

[3] „Mouse PubMed Reference:”. National Center for Biotechnology Information, U.S. National Library of Medicine.

[pmid11099377-4] Götting C, Kuhn J, Zahn R, Brinkmann T, Kleesiek K (децембар 2000). „Molecular cloning and expression of human UDP-d-Xylose:proteoglycan core protein beta-d-xylosyltransferase and its first isoform XT-II”. Journal of Molecular Biology. 304 (4): 517—28. PMID 11099377. doi:10.1006/jmbi.2000.4261.

[entrez-5] „Entrez Gene: XYLT2 xylosyltransferase II”.

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