Гликопротеин-Н-ацетилгалактозамин 3-б-галактозилтрансфераза
| Glikoprotein-N-acetilgalaktozamin 3-b-galaktoziltransferaza | |||||||||
|---|---|---|---|---|---|---|---|---|---|
| Identifikatori | |||||||||
| EC broj | 2.4.1.122 | ||||||||
| CAS broj | 97089-61-7 | ||||||||
| Baze podataka | |||||||||
| IntEnz | IntEnz pregled | ||||||||
| BRENDA | BRENDA pristup | ||||||||
| ExPASy | NiceZyme pregled | ||||||||
| KEGG | KEGG pristup | ||||||||
| MetaCyc | metabolički put | ||||||||
| PRIAM | profil | ||||||||
| Strukture PBP | RCSB PDB PDBe PDBj PDBsum | ||||||||
| |||||||||
Glikoprotein-N-acetilgalaktozamin 3-b-galaktoziltransferaza (EC 2.4.1.122, uridin difosfogalaktoza-mucin beta-(1->3)-galaktoziltransferaza, UDP-galaktoza:glikoprotein-N-acetil-D-galaktozamin 3-beta-D-galaktoziltransferaza) je enzim sa sistematskim imenom UDP-alfa-D-galaktoza:glikoprotein-N-acetil-D-galaktozamin 3-beta-D-galaktoziltransferaza.[1][2][3] Ovaj enzim katalizuje sledeću hemijsku reakciju
- UDP-alfa-D-galaktoza + glikoprotein N-acetil-D-galaktozamin UDP + glikoprotein D-galaktozil-(1->3)-N-acetil-D-galaktozamin
Neredukujući za O-serin-vezani N-acetilgalaktozaminski ostaci mucinskih glikoproteina mogu da budu akceptori.
Reference[уреди | уреди извор]
- ^ Hesford, F.J., Berger, E.G. and van den Eijnden, D.H. (1981). „Identification of the product formed by human erythrocyte galactosyltransferase”. Biochim. Biophys. Acta. 659: 302—311. PMID 6789880.
- ^ Mendicino, J., Sivakami, S., Davila, M. and Chandrasekaran, E.V. (1982). „Purification and properties of UDP-gal:N-acetylgalactosaminide mucin: β1,3-galactosyltransferase from swine trachea mucosa”. J. Biol. Chem. 257: 3987—3994. PMID 6801057.
- ^ Schachter, H., Narasimhan, S., Gleeson, P. and Vella, G. (1983). „Glycosyltransferases involved in elongation of N-glycosidically linked oligosaccharides of the complex or N-acetyllactosamine type”. Methods Enzymol. 98: 98—134. PMID 6366476.
Literatura[уреди | уреди извор]
- Nicholas C. Price; Lewis Stevens (1999). Fundamentals of Enzymology: The Cell and Molecular Biology of Catalytic Proteins (Third изд.). USA: Oxford University Press. ISBN 019850229X.
- Eric J. Toone (2006). Advances in Enzymology and Related Areas of Molecular Biology, Protein Evolution (Volume 75 изд.). Wiley-Interscience. ISBN 0471205036.
- Branden C; Tooze J. Introduction to Protein Structure. New York, NY: Garland Publishing. ISBN 0-8153-2305-0.
- Irwin H. Segel. Enzyme Kinetics: Behavior and Analysis of Rapid Equilibrium and Steady-State Enzyme Systems (Book 44 изд.). Wiley Classics Library. ISBN 0471303097.
Spoljašnje veze[уреди | уреди извор]
- Glycoprotein-N-acetylgalactosamine+3-beta-galactosyltransferase на US National Library of Medicine Medical Subject Headings (MeSH)
