(Skp1-protein)-hidroksiprolin N-acetilglukozaminiltransferaza
| (Skp1-protein)-hidroksiprolin N-acetilglukozaminiltransferaza | |||||||||
|---|---|---|---|---|---|---|---|---|---|
| Identifikatori | |||||||||
| EC broj | 2.4.1.229 | ||||||||
| CAS broj | 256531-81-4 | ||||||||
| Baze podataka | |||||||||
| IntEnz | IntEnz pregled | ||||||||
| BRENDA | BRENDA pristup | ||||||||
| ExPASy | NiceZyme pregled | ||||||||
| KEGG | KEGG pristup | ||||||||
| MetaCyc | metabolički put | ||||||||
| PRIAM | profil | ||||||||
| Strukture PBP | RCSB PDB PDBe PDBj PDBsum | ||||||||
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(Skp1-protein)-hidroksiprolin N-acetilglukozaminiltransferaza (EC 2.4.1.229, Skp1-HyPro GlcNAc-transferaza, UDP-N-acetilglukozamin (GlcNAc):hidroksiprolin polipeptid GlcNAc-transferaza, UDP-GlcNAc:Skp1-hidroksiprolin GlcNAc-transferaza, UDP-GlcNAc:hidroksiprolin polipeptid GlcNAc-transferaza) je enzim sa sistematskim imenom UDP-N-acetil-D-glukozamin:(Skp1-protein)-hidroksiprolin N-acetil-D-glukozaminil-transferaza.[1][2][3] Ovaj enzim katalizuje sledeću hemijsku reakciju
- UDP-N-acetilglukozamin + [Skp1-protein]-hidroksiprolin UDP + [Skp1-protein]-O-(N-acetil-D-glukozaminil)hidroksiprolin
Za dejstvo ovog enzima je neophodan ditiotreitol i divalentni katjon.
Reference
[uredi | uredi izvor]- ^ van der Wel, H., Morris, H.R., Panico, M., Paxton, T., Dell, A., Kaplan, L. and West, C.M. (2002). „Molecular cloning and expression of a UDP-N-acetylglucosamine (GlcNAc):hydroxyproline polypeptide GlcNAc-transferase that modifies Skp1 in the cytoplasm of Dictyostelium”. J. Biol. Chem. 277: 46328—46337. PMID 12244115.
- ^ Teng-umnuay, P., van der Wel, H. and West, C.M. (1999). „Identification of a UDP-GlcNAc:Skp1-hydroxyproline GlcNAc-transferase in the cytoplasm of Dictyostelium”. J. Biol. Chem. 274: 36392—36402. PMID 10593934.
- ^ West, C.M., van der Wel, H. and Gaucher, E.A. (2002). „Complex glycosylation of Skp1 in Dictyostelium: implications for the modification of other eukaryotic cytoplasmic and nuclear proteins”. Glycobiology. 12: 17—17. PMID 11886837.
Literatura
[uredi | uredi izvor]- Nicholas C. Price; Lewis Stevens (1999). Fundamentals of Enzymology: The Cell and Molecular Biology of Catalytic Proteins (Third izd.). USA: Oxford University Press. ISBN 019850229X.
- Eric J. Toone (2006). Advances in Enzymology and Related Areas of Molecular Biology, Protein Evolution (Volume 75 izd.). Wiley-Interscience. ISBN 0471205036.
- Branden C; Tooze J. Introduction to Protein Structure. New York, NY: Garland Publishing. ISBN 0-8153-2305-0.
- Irwin H. Segel. Enzyme Kinetics: Behavior and Analysis of Rapid Equilibrium and Steady-State Enzyme Systems (Book 44 izd.). Wiley Classics Library. ISBN 0471303097.
- William P. Jencks (1987). Catalysis in Chemistry and Enzymology. Dover Publications. ISBN 0486654605.
Spoljašnje veze
[uredi | uredi izvor]- (Skp1-protein)-hydroxyproline+N-acetylglucosaminyltransferase na US National Library of Medicine Medical Subject Headings (MeSH)
