UGT1A6
Appearance
UDP-glukuronoziltransferaza 1-6 je enzim koji je kod ljudi kodiran genom UGT1A6.[4][5][6]
Reference[uredi | uredi izvor]
- ^ a b v GRCm38: Ensembl release 89: ENSMUSG00000090145 - Ensembl, May 2017
- ^ „Human PubMed Reference:”. National Center for Biotechnology Information, U.S. National Library of Medicine.
- ^ „Mouse PubMed Reference:”. National Center for Biotechnology Information, U.S. National Library of Medicine.
- ^ Mackenzie PI, Owens IS, Burchell B, Bock KW, Bairoch A, Bélanger A, Fournel-Gigleux S, Green M, Hum DW, Iyanagi T, Lancet D, Louisot P, Magdalou J, Chowdhury JR, Ritter JK, Schachter H, Tephly TR, Tipton KF, Nebert DW (avgust 1997). „The UDP glycosyltransferase gene superfamily: recommended nomenclature update based on evolutionary divergence”. Pharmacogenetics. 7 (4): 255—69. PMID 9295054. doi:10.1097/00008571-199708000-00001.
- ^ Ritter JK, Chen F, Sheen YY, Tran HM, Kimura S, Yeatman MT, Owens IS (februar 1992). „A novel complex locus UGT1 encodes human bilirubin, phenol, and other UDP-glucuronosyltransferase isozymes with identical carboxyl termini”. The Journal of Biological Chemistry. 267 (5): 3257—61. PMID 1339448. doi:10.1016/S0021-9258(19)50724-4 .
- ^ „Entrez Gene: UGT1A6 UDP glucuronosyltransferase 1 family, polypeptide A6”.
Literatura[uredi | uredi izvor]
- Tukey RH, Strassburg CP (2000). „Human UDP-glucuronosyltransferases: metabolism, expression, and disease”. Annual Review of Pharmacology and Toxicology. 40: 581—616. PMID 10836148. doi:10.1146/annurev.pharmtox.40.1.581.
- King CD, Rios GR, Green MD, Tephly TR (septembar 2000). „UDP-glucuronosyltransferases”. Current Drug Metabolism. 1 (2): 143—61. PMID 11465080. doi:10.2174/1389200003339171.
- Bock KW, Köhle C (2006). „UDP‐Glucuronosyltransferase 1A6: Structural, Functional, and Regulatory Aspects”. UDP-glucuronosyltransferase 1A6: structural, functional, and regulatory aspects. Methods in Enzymology. 400. str. 57—75. ISBN 9780121828059. PMID 16399343. doi:10.1016/S0076-6879(05)00004-2.
- Bosma PJ, Chowdhury JR, Huang TJ, Lahiri P, Elferink RP, Van Es HH, Lederstein M, Whitington PF, Jansen PL, Chowdhury NR (jul 1992). „Mechanisms of inherited deficiencies of multiple UDP-glucuronosyltransferase isoforms in two patients with Crigler-Najjar syndrome, type I”. FASEB Journal. 6 (10): 2859—63. PMID 1634050. S2CID 24007614. doi:10.1096/fasebj.6.10.1634050.
- Ritter JK, Crawford JM, Owens IS (januar 1991). „Cloning of two human liver bilirubin UDP-glucuronosyltransferase cDNAs with expression in COS-1 cells”. The Journal of Biological Chemistry. 266 (2): 1043—7. PMID 1898728. doi:10.1016/S0021-9258(17)35280-8 .
- Harding D, Jeremiah SJ, Povey S, Burchell B (januar 1990). „Chromosomal mapping of a human phenol UDP-glucuronosyltransferase, GNT1”. Annals of Human Genetics. 54 (Pt 1): 17—21. PMID 2108603. S2CID 35661967. doi:10.1111/j.1469-1809.1990.tb00356.x.
- Harding D, Fournel-Gigleux S, Jackson MR, Burchell B (novembar 1988). „Cloning and substrate specificity of a human phenol UDP-glucuronosyltransferase expressed in COS-7 cells”. Proceedings of the National Academy of Sciences of the United States of America. 85 (22): 8381—5. Bibcode:1988PNAS...85.8381H. PMC 282461 . PMID 3141926. doi:10.1073/pnas.85.22.8381 .
- Moghrabi N, Clarke DJ, Boxer M, Burchell B (oktobar 1993). „Identification of an A-to-G missense mutation in exon 2 of the UGT1 gene complex that causes Crigler-Najjar syndrome type 2”. Genomics. 18 (1): 171—3. PMID 8276413. doi:10.1006/geno.1993.1451.
- Aono S, Yamada Y, Keino H, Hanada N, Nakagawa T, Sasaoka Y, Yazawa T, Sato H, Koiwai O (decembar 1993). „Identification of defect in the genes for bilirubin UDP-glucuronosyl-transferase in a patient with Crigler-Najjar syndrome type II”. Biochemical and Biophysical Research Communications. 197 (3): 1239—44. PMID 8280139. doi:10.1006/bbrc.1993.2610.
- Killard AJ, O'Kennedy R, Bogan DP (avgust 1996). „Analysis of the glucuronidation of 7-hydroxycoumarin by HPLC”. Journal of Pharmaceutical and Biomedical Analysis. 14 (11): 1585—90. PMID 8877866. doi:10.1016/0731-7085(96)01801-8.
- Bonaldo MF, Lennon G, Soares MB (septembar 1996). „Normalization and subtraction: two approaches to facilitate gene discovery”. Genome Research. 6 (9): 791—806. PMID 8889548. doi:10.1101/gr.6.9.791 .
- Ciotti M, Marrone A, Potter C, Owens IS (decembar 1997). „Genetic polymorphism in the human UGT1A6 (planar phenol) UDP-glucuronosyltransferase: pharmacological implications”. Pharmacogenetics. 7 (6): 485—95. PMID 9429234. doi:10.1097/00008571-199712000-00007.
- Münzel PA, Lehmköster T, Brück M, Ritter JK, Bock KW (februar 1998). „Aryl hydrocarbon receptor-inducible or constitutive expression of human UDP glucuronosyltransferase UGT1A6”. Archives of Biochemistry and Biophysics. 350 (1): 72—8. PMID 9466822. doi:10.1006/abbi.1997.0485.
- Duffy CF, O'Kennedy R (septembar 1998). „Determination of 7-hydroxycoumarin and its glucuronide and sulphate conjugates in liver slice incubates by capillary zone electrophoresis”. Journal of Pharmaceutical and Biomedical Analysis. 17 (8): 1279—84. PMID 9800648. doi:10.1016/S0731-7085(98)00015-6.
- Gong QH, Cho JW, Huang T, Potter C, Gholami N, Basu NK, Kubota S, Carvalho S, Pennington MW, Owens IS, Popescu NC (jun 2001). „Thirteen UDPglucuronosyltransferase genes are encoded at the human UGT1 gene complex locus”. Pharmacogenetics. 11 (4): 357—68. PMID 11434514. doi:10.1097/00008571-200106000-00011.