Galaktozid 3-fukoziltransferaza
Изглед
Galaktozid 3-fukoziltransferaza | |||||||||
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Identifikatori | |||||||||
EC broj | 2.4.1.152 | ||||||||
CAS broj | 39279-34-0 | ||||||||
Baze podataka | |||||||||
IntEnz | IntEnz pregled | ||||||||
BRENDA | BRENDA pristup | ||||||||
ExPASy | NiceZyme pregled | ||||||||
KEGG | KEGG pristup | ||||||||
MetaCyc | metabolički put | ||||||||
PRIAM | profil | ||||||||
Strukture PBP | RCSB PDB PDBe PDBj PDBsum | ||||||||
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Galaktozid 3-fukoziltransferaza (EC 2.4.1.152, Luisova negativna alfa-3-fukoziltransferaza, plazma alfa-3-fukoziltransferaza, guanozin difosfofukoza-glukozid alfa1->3-fukoziltransferaza, GDP-L-fukoza:1,4-beta-D-galaktozil-N-acetil-D-glukozaminil-R 3-L-fukoziltransferaza, GDP-beta-L-fukoza:1,4-beta-D-galaktozil-N-acetil-D-glukozaminil-R 3-L-fukoziltransferaza, GDP-beta-L-fukoza:1,4-beta-D-galaktozil-N-acetil-D-glukozaminil-R 3-alfa-L-fukoziltransferaza) je enzim sa sistematskim imenom GDP-beta-L-fukoza:(1->4)-beta-D-galaktozil-N-acetil-D-glukozaminil-R 3-alfa-L-fukoziltransferaza.[1][2][3] Ovaj enzim katalizuje sledeću hemijsku reakciju
- GDP-beta-L-fukoza + (1->4)-beta-D-galaktozil-N-acetil-D-glukozaminil-R GDP + (1->4)-beta-D-galaktozil-[alfa-(1->3)-L-fukozil]-N-acetil-D-glukozaminil-R
Ovaj enzim normalno deluje na glikokonjugate, gde je R glikoprotein ili glikolipid.
Reference[уреди | уреди извор]
- ^ Johnson, P.H., Yates, A.D. and Watkins, W.M. (1981). „Human salivary fucosyltransferase: evidence for two distinct α-3-L-fucosyltransferase activities one of which is associated with the Lewis blood Le gene”. Biochem. Biophys. Res. Commun. 100: 1611—1618. PMID 7295318.
- ^ Schachter, H., Narasimhan, S., Gleeson, P. and Vella, G. (1983). „Glycosyltransferases involved in elongation of N-glycosidically linked oligosaccharides of the complex or N-acetyllactosamine type”. Methods Enzymol. 98: 98—134. PMID 6366476.
- ^ Ma, B., Wang, G., Palcic, M.M., Hazes, B. and Taylor, D.E. (2003). „C-terminal amino acids of Helicobacter pylori α1,3/4 fucosyltransferases determine type I and type II transfer”. J. Biol. Chem. 278: 21893—21900. PMID 12676935.
Literatura[уреди | уреди извор]
- Nicholas C. Price; Lewis Stevens (1999). Fundamentals of Enzymology: The Cell and Molecular Biology of Catalytic Proteins (Third изд.). USA: Oxford University Press. ISBN 019850229X.
- Eric J. Toone (2006). Advances in Enzymology and Related Areas of Molecular Biology, Protein Evolution (Volume 75 изд.). Wiley-Interscience. ISBN 0471205036.
- Branden C; Tooze J. Introduction to Protein Structure. New York, NY: Garland Publishing. ISBN 0-8153-2305-0.
- Irwin H. Segel. Enzyme Kinetics: Behavior and Analysis of Rapid Equilibrium and Steady-State Enzyme Systems (Book 44 изд.). Wiley Classics Library. ISBN 0471303097.
Spoljašnje veze[уреди | уреди извор]
- 4-galactosyl-N-acetylglucosaminide+3-alpha-L-fucosyltransferase на US National Library of Medicine Medical Subject Headings (MeSH)