Laktozilkeramid a-2,6-N-sijaliltransferaza
Изглед
Laktozilkeramid a-2,6-N-sijaliltransferaza | |||||||||
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Identifikatori | |||||||||
EC broj | 2.4.99.11 | ||||||||
CAS broj | 55071-95-9 | ||||||||
Baze podataka | |||||||||
IntEnz | IntEnz pregled | ||||||||
BRENDA | BRENDA pristup | ||||||||
ExPASy | NiceZyme pregled | ||||||||
KEGG | KEGG pristup | ||||||||
MetaCyc | metabolički put | ||||||||
PRIAM | profil | ||||||||
Strukture PBP | RCSB PDB PDBe PDBj PDBsum | ||||||||
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Laktozilkeramid a-2,6-N-sijaliltransferaza (EC 2.4.99.11, citidin monofosfoacetilneuraminat-laktozilkeramid sijaliltransferaza, CMP-acetilneuraminat-laktozilkeramid-sijaliltransferaza, CMP-N-acetilneuraminska kiselina:laktozilkeramid sijaliltransferaza, CMP-sijalinska kiselina:laktozilkeramid sijaliltransferaza, CMP-N-acetilneuraminat:laktozilkeramid alfa-2,6-N-acetilneuraminiltransferaza, CMP-N-acetilneuraminat:beta-D-galaktozil-(1->4)-beta-D-glukozil(1<->1)keramid alfa-(2->6)-N-acetilneuraminiltransferaza) je enzim sa sistematskim imenom CMP-N-acetilneuraminat:beta-D-galaktozil-(1->4)-beta-D-glukozil-(1<->1)-keramid alfa-(2->6)-N-acetilneuraminiltransferaza.[1][2] Ovaj enzim katalizuje sledeću hemijsku reakciju
- CMP-N-acetilneuraminat + beta-D-galaktozil-(1->4)-beta-D-glukozil-(1<->1)-keramid CMP + alfa-N-acetilneuraminil-(2->6)-beta-D-galaktozil-(1->4)-beta-D-glukozil-(1<->1)-keramid
Reference
[уреди | уреди извор]- ^ Albarracin, I., Lassaga, F.E. and Caputto, R. (1988). „Purification and characterization of an endogenous inhibitor of the sialyltransferase CMP-N-acetylneuraminate: lactosylceramide α2,6-N-acetylneuraminyltransferase (EC 2.4.99.-)”. Biochem. J. 254: 559—565. PMID 2460092.
- ^ Landa, C.A., Maccioni, H.J.F., Arce, A. and Caputto, R. (1977). „The biosynthesis of brain gangliosides. Separation of membranes with different ratios of ganglioside sialylating activity to gangliosides”. Biochem. J. 168: 325—332. PMID 606237.
Literatura
[уреди | уреди извор]- Nicholas C. Price; Lewis Stevens (1999). Fundamentals of Enzymology: The Cell and Molecular Biology of Catalytic Proteins (Third изд.). USA: Oxford University Press. ISBN 019850229X.
- Eric J. Toone (2006). Advances in Enzymology and Related Areas of Molecular Biology, Protein Evolution (Volume 75 изд.). Wiley-Interscience. ISBN 0471205036.
- Branden C; Tooze J. Introduction to Protein Structure. New York, NY: Garland Publishing. ISBN 0-8153-2305-0.
- Irwin H. Segel. Enzyme Kinetics: Behavior and Analysis of Rapid Equilibrium and Steady-State Enzyme Systems (Book 44 изд.). Wiley Classics Library. ISBN 0471303097.
- William P. Jencks (1987). Catalysis in Chemistry and Enzymology. Dover Publications. ISBN 0486654605.
Spoljašnje veze
[уреди | уреди извор]- Lactosylceramide+alpha-2,6-N-sialyltransferase на US National Library of Medicine Medical Subject Headings (MeSH)