Metionin-S-oksid reduktaza
| Metionin-S-oksid reduktaza | |||||||||
|---|---|---|---|---|---|---|---|---|---|
| Identifikatori | |||||||||
| EC broj | 1.8.4.5 | ||||||||
| CAS broj | 70248-65-6 | ||||||||
| Baze podataka | |||||||||
| IntEnz | IntEnz pregled | ||||||||
| BRENDA | BRENDA pristup | ||||||||
| ExPASy | NiceZyme pregled | ||||||||
| KEGG | KEGG pristup | ||||||||
| MetaCyc | metabolički put | ||||||||
| PRIAM | profil | ||||||||
| Strukture PBP | RCSB PDB PDBe PDBj PDBsum | ||||||||
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Metionin-S-oksid reduktaza (EC 1.8.4.5, metil sulfoksidna reduktaza I i II, acetilmetionin sulfoksidna reduktaza, metionin sulfoksidna reduktaza, L-metionin:oksidovani-tioredoksin S-oksidoreduktaza) je enzim sa sistematskim imenom L-metionin:tioredoksin-disulfid S-oksidoreduktaza.[1][2][3] Ovaj enzim katalizuje sledeću hemijsku reakciju
- L-metionin + tioredoksin disulfid + H2O L-metionin S-oksid + tioredoksin
U reverznoj reakciji, ditiotreitol može da zameni redukovani tioredoksin.
Reference[уреди | уреди извор]
- ^ Black, S., Harte, E.M., Hudson, B. and Wartofsky, L. (1960). „A specific enzymatic reduction of L-(-)methionine sulfoxide and a related nonspecific reduction of diulfides”. J. Biol. Chem. 235: 2910—2916.
- ^ Ejiri, S.-I., Weissbach, H. and Brot, N. (1979). „Reduction of methionine sulfoxide to methionine by Escherichia coli”. J. Bacteriol. 139: 161—164. PMID 37234.
- ^ Ejiri, S.-I., Weissbach, H. and Brot, N. (1980). „The purification of methionine sulfoxide reductase from Escherichia coli”. Anal. Biochem. 102: 393—398. PMID 6999943.
Literatura[уреди | уреди извор]
- Nicholas C. Price; Lewis Stevens (1999). Fundamentals of Enzymology: The Cell and Molecular Biology of Catalytic Proteins (Third изд.). USA: Oxford University Press. ISBN 019850229X.
- Eric J. Toone (2006). Advances in Enzymology and Related Areas of Molecular Biology, Protein Evolution (Volume 75 изд.). Wiley-Interscience. ISBN 0471205036.
- Branden C; Tooze J. Introduction to Protein Structure. New York, NY: Garland Publishing. ISBN 0-8153-2305-0.
- Irwin H. Segel. Enzyme Kinetics: Behavior and Analysis of Rapid Equilibrium and Steady-State Enzyme Systems (Book 44 изд.). Wiley Classics Library. ISBN 0471303097.
- William P. Jencks (1987). Catalysis in Chemistry and Enzymology. Dover Publications. ISBN 0486654605.
Spoljašnje veze[уреди | уреди извор]
- Methionine-S-oxide+reductase на US National Library of Medicine Medical Subject Headings (MeSH)
