Protein N-acetilglukozaminiltransferaza
| Protein N-acetilglukozaminiltransferaza | |||||||||
|---|---|---|---|---|---|---|---|---|---|
| Identifikatori | |||||||||
| EC broj | 2.4.1.94 | ||||||||
| CAS broj | 72319-34-7 | ||||||||
| Baze podataka | |||||||||
| IntEnz | IntEnz pregled | ||||||||
| BRENDA | BRENDA pristup | ||||||||
| ExPASy | NiceZyme pregled | ||||||||
| KEGG | KEGG pristup | ||||||||
| MetaCyc | metabolički put | ||||||||
| PRIAM | profil | ||||||||
| Strukture PBP | RCSB PDB PDBe PDBj PDBsum | ||||||||
| |||||||||
Protein N-acetilglukozaminiltransferaza (EC 2.4.1.94, uridin difosfoacetilglukozamin-protein acetilglukozaminiltransferaza, uridin difosfo-N-acetilglukozamin:polipeptid beta-N-acetilglukozaminiltransferaza, N-acetilglukozaminiltransferaza I) je enzim sa sistematskim imenom UDP-N-acetil-D-glukozamin:(protein)-L-asparagin beta-N-acetil-D-glukozaminil-transferaza.[1][2][3] Ovaj enzim katalizuje sledeću hemijsku reakciju
- UDP-N-acetil-D-glukozamin + [protein]-L-asparagin UDP + [protein]-N4-(N-acetil-D-glukozaminil)-L-asparagin
Akceptor je asparaginski ostatak u sequenci oblika Asn-Xaa-Thr or Asn-Xaa-Ser.
Reference[уреди | уреди извор]
- ^ Khalkhali, Z. & Marshall, R.D. (1975). „Glycosylation of ribonuclease A catalysed by rabbit liver extracts”. Biochem. J. 146: 299—307. PMID 1156375.
- ^ Khalkhali, Z. & Marshall, R.D. (1976). „UDP-N-acetyl-D-glucosamine-asparagine sequon N-acetyl-β-D-glucosaminyl-transferase-activity in human serum”. Carbohydr. Res. 49: 455—473. PMID 986874.
- ^ Khalkhali, Z., Marshall, R.D., Reuvers, F., Habets-Willems, C. and Boer, P. (1976). „Glycosylation in vitro of an asparagine sequon catalysed by preparations of yeast cell membranes”. Biochem. J. 160: 37—41. PMID 795426.
Literatura[уреди | уреди извор]
- Nicholas C. Price; Lewis Stevens (1999). Fundamentals of Enzymology: The Cell and Molecular Biology of Catalytic Proteins (Third изд.). USA: Oxford University Press. ISBN 019850229X.
- Eric J. Toone (2006). Advances in Enzymology and Related Areas of Molecular Biology, Protein Evolution (Volume 75 изд.). Wiley-Interscience. ISBN 0471205036.
- Branden C; Tooze J. Introduction to Protein Structure. New York, NY: Garland Publishing. ISBN 0-8153-2305-0.
- Irwin H. Segel. Enzyme Kinetics: Behavior and Analysis of Rapid Equilibrium and Steady-State Enzyme Systems (Book 44 изд.). Wiley Classics Library. ISBN 0471303097.
- William P. Jencks (1987). Catalysis in Chemistry and Enzymology. Dover Publications. ISBN 0486654605.
Spoljašnje veze[уреди | уреди извор]
- Protein+N-acetylglucosaminyltransferase на US National Library of Medicine Medical Subject Headings (MeSH)
