Saharoza—1,6-a-glukan 3(6)-a-glukoziltransferaza
| Saharoza—1,6-a-glukan 3(6)-a-glukoziltransferaza | |||||||||
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| Identifikatori | |||||||||
| EC broj | 2.4.1.125 | ||||||||
| CAS broj | 81725-87-3 | ||||||||
| Baze podataka | |||||||||
| IntEnz | IntEnz pregled | ||||||||
| BRENDA | BRENDA pristup | ||||||||
| ExPASy | NiceZyme pregled | ||||||||
| KEGG | KEGG pristup | ||||||||
| MetaCyc | metabolički put | ||||||||
| PRIAM | profil | ||||||||
| Strukture PBP | RCSB PDB PDBe PDBj PDBsum | ||||||||
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Saharoza—1,6-a-glukan 3(6)-a-glukoziltransferaza (EC 2.4.1.125, u vodi rastvorna glukanska sintaza, GTF-I, GTF-S, GTF-SI, saharoza-1,6-alfa-glukan 3(6)-alfa-glukoziltransferaza, saharoza:1,6-alfa-D-glukan 3-alfa- and 6-alfa-glukoziltransferaza, saharoza:1,6-, 1,3-alfa-D-glukan 3-alfa- and 6-alfa-D-glukoziltransferaza, saharoza:1,6-alfa-D-glukan 3(6)-alfa-D-glukoziltransferaza, gtfB (gen), gtfC (gen), gtfD (gen)) je enzim sa sistematskim imenom saharoza:(1->6)-alfa-D-glukan 3(6)-alfa-D-glukoziltransferaza.[1][2][3][4][5][6] Ovaj enzim katalizuje sledeću hemijsku reakciju
- (1) saharoza + [(1->6)-alfa-D-glukozil]n D-fruktoza + [(1->6)-alfa-D-glukozil]n+1
- (2) saharoza + [(1->6)-alfa-D-glukozil]n D-fruktoza + (1->3)-alfa-D-glukozil[(1->6)-alfa-D-glukozil]n
Ovaj enzim je izolovan iz bakterije dentalnog karijesa Streptococcus mutans.
Reference[уреди | уреди извор]
- ^ Mukasa, H., Shimamura, A. and Tsumori, H. (1982). „Purification and characterization of basic glucosyltransferase from Streptococcus mutans serotype c”. Biochim. Biophys. Acta. 719: 81—89. PMID 6216919.
- ^ Shimamura, A., Tsumori, H. and Mukasa, H. (1982). „Purification and properties of Streptococcus mutans extracellular glucosyltransferase”. Biochim. Biophys. Acta. 702: 72—80. PMID 6461359.
- ^ Tsumori, H., Shimamura, A. and Mukasa, H. (1985). „Purification and properties of extracellular glucosyltransferase synthesizing 1,6-, 1,3-α-D-glucan from Streptococcus mutans serotype a”. J. Gen. Microbiol. 131: 3347—3353. PMID 2937877.
- ^ Fujiwara, T., Tamesada, M., Bian, Z., Kawabata, S., Kimura, S. and Hamada, S. (1996). „Deletion and reintroduction of glucosyltransferase genes of Streptococcus mutans and role of their gene products in sucrose dependent cellular adherence”. Microb Pathog. 20: 225—233. PMID 8737492.
- ^ Monchois, V., Willemot, R.M. and Monsan, P. (1999). „Glucansucrases: mechanism of action and structure-function relationships”. FEMS Microbiol. Rev. 23: 131—151. PMID 10234842.
- ^ Ito, K., Ito, S., Shimamura, T., Weyand, S., Kawarasaki, Y., Misaka, T., Abe, K., Kobayashi, T., Cameron, A.D. and Iwata, S. (2011). „Crystal structure of glucansucrase from the dental caries pathogen Streptococcus mutans”. J. Mol. Biol. 408: 177—186. PMID 21354427.
Literatura[уреди | уреди извор]
- Nicholas C. Price; Lewis Stevens (1999). Fundamentals of Enzymology: The Cell and Molecular Biology of Catalytic Proteins (Third изд.). USA: Oxford University Press. ISBN 019850229X.
- Eric J. Toone (2006). Advances in Enzymology and Related Areas of Molecular Biology, Protein Evolution (Volume 75 изд.). Wiley-Interscience. ISBN 0471205036.
- Branden C; Tooze J. Introduction to Protein Structure. New York, NY: Garland Publishing. ISBN 0-8153-2305-0.
- Irwin H. Segel. Enzyme Kinetics: Behavior and Analysis of Rapid Equilibrium and Steady-State Enzyme Systems (Book 44 изд.). Wiley Classics Library. ISBN 0471303097.
Spoljašnje veze[уреди | уреди извор]
- Sucrose—1,6-alpha-glucan+3(6)-alpha-glucosyltransferase на US National Library of Medicine Medical Subject Headings (MeSH)
